Institut Pasteur: Introductions and early spread of SARS-CoV-2 in France

[sharon sanders]

des nouvelles du jour :
"Une ?tude g?n?tique men?e par l'Institut Pasteur laisse entendre que la diffusion de l'?pid?mie dans l'Hexagone serait pour tr?s peu li?e ? des cas import?s de Chine ou d'Italie. Une troisi?me souche ? l'origine pour l'instant inconnue expliquerait la forte diffusion de l'?pid?mie dans l'Hexagone."
https://www.lesechos.fr/economie-fra...italie-1199167

Introductions and early spread of SARS-CoV-2 in France

Fabiana G?mbaro, Sylvie Behillil, Artem Baidaliuk, Flora Donati, M?lanie Albert, Andreea Alexandru, Maud Vanpeene, M?line Bizard, Angela Brisebarre, M arion Barbet, Fawzi Derrar, Sylvie van der Werf, Vincent Enouf, View ORCID ProfileEtienne Simon-Loriere
doi: https://doi.org/10.1101/2020.04.24.059576
This article is a preprint and has not been certified by peer review [what does this mean?].

• Abstract
• Full Text
• Info/History
• Metrics
• Preview PDF

Abstract


Following the emergence of coronavirus disease (COVID-19) in Wuhan, China in December 2019, specific COVID-19 surveillance was launched in France on January 10, 2020. Two weeks later, the first three imported cases of COVID-19 into Europe were diagnosed in France. We sequenced 97 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes from samples collected between January 24 and March 24, 2020 from infected patients in France. Phylogenetic analysis identified several early independent SARS-CoV-2 introductions without local transmission, highlighting the efficacy of the measures taken to prevent virus spread from symptomatic cases. In parallel, our genomic data reveals the later predominant circulation of a major clade in many French regions, and implies local circulation of the virus in undocumented infections prior to the wave of COVID-19 cases. This study emphasizes the importance continuous and geographically broad genomic sequencing and calls for further efforts with inclusion of asymptomatic infections.


https://www.biorxiv.org/content/10.1...04.24.059576v1

 

[gsgs]

the sequences are apparently only at gisaid. I saw this some days ago at virological.org . There was a paper about the Oise-cluster,
no keyword hit for "oise" in this paper here
Oise:5,10,15,20,30 seropositive on highschool with onset in week 3[Jan12-Jan18?],4,5,6,7
One superspreader from Singapur-->Alpes-->Brighton , English sequences sampled Feb14,15,16,18, see wiki
https://en.wikipedia.org/wiki/2020_coronavirus_pandemic_in_France#Les_Contamines-Montjoie_cluster