tetano
Editor, Senior Moderator
Int J Infect Dis
. 2022 Jan 18;S1201-9712(22)00027-3.
doi: 10.1016/j.ijid.2022.01.027. Online ahead of print.
Constrictive pericarditis after SARS-CoV-2 vaccination: A case report
Yuki Nakanishi[SUP] 1 [/SUP], Sakiko Honda[SUP] 2 [/SUP], Michiyo Yamano[SUP] 1 [/SUP], Tatsuya Kawasaki[SUP] 1 [/SUP], Keiji Yoshioka[SUP] 3 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) and vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are associated with cardiovascular complications. We report a case of right-sided heart failure due to constrictive pericarditis that developed after administration of messenger ribonucleic acid (mRNA) vaccines against SARS-CoV-2. A 70-year-old woman presented with body weight gain, peripheral edema, and dyspnea on effort, which developed over a period of one week after the second vaccine injection. The jugular venous pressure was high with a prominent y descent (Friedreich's sign) and paradoxical increase on inspiration (Kussmaul's sign). The results of IgM and IgG testing specific to SARS-CoV-2 spike and nucleocapsid proteins were consistent with mRNA vaccine-induced antibody, not COVID-19 infection. Echocardiography demonstrated pericardial thickening and septal bounce of the interventricular septum. Computed tomography also revealed pericardial thickening compared with the previous examination four months earlier. A diagnosis of right-sided heart failure due to constrictive pericarditis was confirmed based on pressure analysis during cardiac catheterization.
Keywords: COVID-19; Constrictive pericarditis; SARS-CoV-2; vaccination.
. 2022 Jan 18;S1201-9712(22)00027-3.
doi: 10.1016/j.ijid.2022.01.027. Online ahead of print.
Constrictive pericarditis after SARS-CoV-2 vaccination: A case report
Yuki Nakanishi[SUP] 1 [/SUP], Sakiko Honda[SUP] 2 [/SUP], Michiyo Yamano[SUP] 1 [/SUP], Tatsuya Kawasaki[SUP] 1 [/SUP], Keiji Yoshioka[SUP] 3 [/SUP]
Affiliations
- PMID: 35063679
- DOI: 10.1016/j.ijid.2022.01.027
Abstract
Coronavirus disease 2019 (COVID-19) and vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are associated with cardiovascular complications. We report a case of right-sided heart failure due to constrictive pericarditis that developed after administration of messenger ribonucleic acid (mRNA) vaccines against SARS-CoV-2. A 70-year-old woman presented with body weight gain, peripheral edema, and dyspnea on effort, which developed over a period of one week after the second vaccine injection. The jugular venous pressure was high with a prominent y descent (Friedreich's sign) and paradoxical increase on inspiration (Kussmaul's sign). The results of IgM and IgG testing specific to SARS-CoV-2 spike and nucleocapsid proteins were consistent with mRNA vaccine-induced antibody, not COVID-19 infection. Echocardiography demonstrated pericardial thickening and septal bounce of the interventricular septum. Computed tomography also revealed pericardial thickening compared with the previous examination four months earlier. A diagnosis of right-sided heart failure due to constrictive pericarditis was confirmed based on pressure analysis during cardiac catheterization.
Keywords: COVID-19; Constrictive pericarditis; SARS-CoV-2; vaccination.
