tetano
Editor, Senior Moderator
Intern Med
. 2020 Aug 29.
doi: 10.2169/internalmedicine.5413-20. Online ahead of print.
Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion
Yusaku Kusaba[SUP] 1 [/SUP], Shinyu Izumi[SUP] 1 [/SUP], Jin Takasaki[SUP] 1 [/SUP], Manabu Suzuki[SUP] 1 [/SUP], Daisuke Katagiri[SUP] 2 [/SUP], Takashi Katsuno[SUP] 1 [/SUP], Shuichiro Matsumoto[SUP] 1 [/SUP], Keita Sakamoto[SUP] 1 [/SUP], Masao Hashimoto[SUP] 1 [/SUP], Norio Ohmagari[SUP] 3 [/SUP], Harutaka Katano[SUP] 4 [/SUP], Tadaki Suzuki[SUP] 4 [/SUP], Masayuki Hojo[SUP] 1 [/SUP], Haruhito Sugiyama[SUP] 1 [/SUP]
Affiliations
Abstract
An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung.
Keywords: COVID-19; SARS-CoV-2; acute respiratory failure; polymyxin B-immobilized fiber column-direct hemoperfusion.
. 2020 Aug 29.
doi: 10.2169/internalmedicine.5413-20. Online ahead of print.
Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion
Yusaku Kusaba[SUP] 1 [/SUP], Shinyu Izumi[SUP] 1 [/SUP], Jin Takasaki[SUP] 1 [/SUP], Manabu Suzuki[SUP] 1 [/SUP], Daisuke Katagiri[SUP] 2 [/SUP], Takashi Katsuno[SUP] 1 [/SUP], Shuichiro Matsumoto[SUP] 1 [/SUP], Keita Sakamoto[SUP] 1 [/SUP], Masao Hashimoto[SUP] 1 [/SUP], Norio Ohmagari[SUP] 3 [/SUP], Harutaka Katano[SUP] 4 [/SUP], Tadaki Suzuki[SUP] 4 [/SUP], Masayuki Hojo[SUP] 1 [/SUP], Haruhito Sugiyama[SUP] 1 [/SUP]
Affiliations
- PMID: 32863364
- DOI: 10.2169/internalmedicine.5413-20
Abstract
An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung.
Keywords: COVID-19; SARS-CoV-2; acute respiratory failure; polymyxin B-immobilized fiber column-direct hemoperfusion.