tetano
Editor, Senior Moderator
J Appl Microbiol
. 2023 Jul 14;lxad147.
doi: 10.1093/jambio/lxad147. Online ahead of print. In vitro Inactivation of SARS-CoV-2 by Ozonated Water Via Novel Hand Hygiene Device
Robert M Lubitz[SUP] 1 [/SUP], Brian R Leon[SUP] 1 [/SUP], K Nicole Bradner[SUP] 2 [/SUP], Daniel J Romary[SUP] 1 [/SUP], Sarah A Landsberger[SUP] 1 [/SUP]
Affiliations
Aims: The COVID-19 Pandemic has heightened awareness of the need for novel surface disinfectants and hand-hygiene modalities. Ozone gas is an effective surface disinfectant, but toxicity limits its use in human applications. Ozonated water is a safer means to use ozone for disinfection, especially for human antisepsis. However, there are little data available regarding the effectiveness of ozonated water in eliminating severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Methods & results: This study utilizes a novel hand hygiene device that produces a stable ozone concentration of 0.5 +/- 0.1 ppm in water and applies it using a proprietary spray that controls droplet size, velocity, and direction. The Device was used to apply ozonated water to a known quantity of SARS-CoV-2 Delta Variant viral particles on a non-porous surface (glass) for seven seconds. Post-exposure growth was compared to the unexposed matched control utilizing the Spearman-Karber method. Compared to control, ozonated water decreased SARS-CoV-2 viral growth by a mean log10 reduction of 4.33, or > 99.99% reduction.
Conclusions: These results suggest that the ozonated water, when applied by a spray hand hygiene device, is highly effective at surface disinfection of SARS-CoV-2.
. 2023 Jul 14;lxad147.
doi: 10.1093/jambio/lxad147. Online ahead of print. In vitro Inactivation of SARS-CoV-2 by Ozonated Water Via Novel Hand Hygiene Device
Robert M Lubitz[SUP] 1 [/SUP], Brian R Leon[SUP] 1 [/SUP], K Nicole Bradner[SUP] 2 [/SUP], Daniel J Romary[SUP] 1 [/SUP], Sarah A Landsberger[SUP] 1 [/SUP]
Affiliations
- PMID: 37451808
- DOI: 10.1093/jambio/lxad147
Aims: The COVID-19 Pandemic has heightened awareness of the need for novel surface disinfectants and hand-hygiene modalities. Ozone gas is an effective surface disinfectant, but toxicity limits its use in human applications. Ozonated water is a safer means to use ozone for disinfection, especially for human antisepsis. However, there are little data available regarding the effectiveness of ozonated water in eliminating severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Methods & results: This study utilizes a novel hand hygiene device that produces a stable ozone concentration of 0.5 +/- 0.1 ppm in water and applies it using a proprietary spray that controls droplet size, velocity, and direction. The Device was used to apply ozonated water to a known quantity of SARS-CoV-2 Delta Variant viral particles on a non-porous surface (glass) for seven seconds. Post-exposure growth was compared to the unexposed matched control utilizing the Spearman-Karber method. Compared to control, ozonated water decreased SARS-CoV-2 viral growth by a mean log10 reduction of 4.33, or > 99.99% reduction.
Conclusions: These results suggest that the ozonated water, when applied by a spray hand hygiene device, is highly effective at surface disinfection of SARS-CoV-2.