J Eur Acad Dermatol Venereol . SARS-CoV-2 spike protein is present in both endothelial and eccrine cells of a chilblain-like skin lesion

[tetano]

J Eur Acad Dermatol Venereol


. 2020 Oct 1.
doi: 10.1111/jdv.16970. Online ahead of print.
SARS-CoV-2 spike protein is present in both endothelial and eccrine cells of a chilblain-like skin lesion


T Gambichler[SUP] 1 [/SUP], J Reuther[SUP] 1 [/SUP], M St?cker[SUP] 1 [/SUP], R Stranzenbach[SUP] 1 [/SUP], C Torres-Reyes[SUP] 2 [/SUP], R Schlottmann[SUP] 2 [/SUP], W E Schmidt[SUP] 2 [/SUP], R Hayajneh[SUP] 3 4 [/SUP], A Sriram[SUP] 3 4 [/SUP], J C Becker[SUP] 3 4 [/SUP]



Affiliations

• PMID: 33002210
• DOI: 10.1111/jdv.16970

Abstract

Data on SARS-CoV-2 detection in lesional skin is controversial.[SUP]1-8[/SUP] We report a PCR-proven COVID-19 patient with a chilblain-like SARS-CoV-2 positive skin lesion. An 80-year-old woman presented to the emergency department at the End of March 2020. She reported an onset of fever (38.4 C?) several days before admission, along with cough and shortness of breath. RT-PCR from a nasopharyngeal swab was positive for SARS-CoV-2. An X-ray showed evidence for right-sided pneumonic infiltrates.

Keywords: COVID-19; SARS-CoV-2; coronavirus; eccrine glands; endothelial cells; spike protein.