tetano
Editor, Senior Moderator
J Infect Public Health
. 2020 Jun 19;S1876-0341(20)30523-2.
doi: 10.1016/j.jiph.2020.06.013. Online ahead of print.
Public Health Initiatives From Hospitalized Patients With COVID-19, China
Chenkai Zhao[SUP] 1 [/SUP], Yueqin Xu[SUP] 2 [/SUP], Xu Zhang[SUP] 2 [/SUP], Yaping Zhong[SUP] 1 [/SUP], Li Long[SUP] 3 [/SUP], Wenzhi Zhan[SUP] 3 [/SUP], Tingting Xu[SUP] 3 [/SUP], Chen Zhan[SUP] 3 [/SUP], Yuehan Chen[SUP] 3 [/SUP], Jinghai Zhu[SUP] 1 [/SUP], Wei Xiao[SUP] 4 [/SUP], Miao He[SUP] 5 [/SUP]
Affiliations
Abstract
Background: Since December 2019, when it first occurred in Wuhan, China, coronavirus disease 2019 (COVID-19) has spread rapidly worldwide via human-to-human transmission. We aimed to describe the epidemiological and demographic features of COVID-19 outside Wuhan.
Methods: A single-center case series of 136 consecutive (from January 16 to February 17, 2020) patients with confirmed COVID-19 hospitalized in The First People's Hospital of Jingzhou, China, was retrospectively analyzed. Outcomes were followed up until February 19, 2020.
Results: Of the 136 patients (median age, 49 years; interquartile range [IQR], 33-63 years; range, 0.3-83 years), 91 (67%) had been to Wuhan or contacted persons from Wuhan. Forty-five (33.1%) were familial clusters. The median incubation period was 6 days (IQR: 4-11 days). All children had an exact exposure history, family members with COVID-19, and "Mild/Moderate" symptoms at admission. Among the 64 elderly patients, 14 (21.9%) had no exposure history, and 43 (67.2%) had a chronic illness. All 11 (8.1%) "Severe/very severe" illness at onset cases and 5 (3.7%) fatal cases were elderly patients. The duration from symptom onset to admission was positively correlated with the duration from symptom onset to endpoint. Overall, patients with a longer incubation period had more severe outcomes.
Conclusion: As high-risk susceptible groups, strong protection should be implemented for children and the elderly. Universal screening should be performed for people with a clear exposure history, even lacking apparent symptoms. Given the rapid progression of COVID-19, people should be admitted quickly following symptom onset.
Keywords: China; Coronavirus disease 2019; Epidemiology; High-risk susceptible people; Incubation period.
. 2020 Jun 19;S1876-0341(20)30523-2.
doi: 10.1016/j.jiph.2020.06.013. Online ahead of print.
Public Health Initiatives From Hospitalized Patients With COVID-19, China
Chenkai Zhao[SUP] 1 [/SUP], Yueqin Xu[SUP] 2 [/SUP], Xu Zhang[SUP] 2 [/SUP], Yaping Zhong[SUP] 1 [/SUP], Li Long[SUP] 3 [/SUP], Wenzhi Zhan[SUP] 3 [/SUP], Tingting Xu[SUP] 3 [/SUP], Chen Zhan[SUP] 3 [/SUP], Yuehan Chen[SUP] 3 [/SUP], Jinghai Zhu[SUP] 1 [/SUP], Wei Xiao[SUP] 4 [/SUP], Miao He[SUP] 5 [/SUP]
Affiliations
- PMID: 32591163
- DOI: 10.1016/j.jiph.2020.06.013
Abstract
Background: Since December 2019, when it first occurred in Wuhan, China, coronavirus disease 2019 (COVID-19) has spread rapidly worldwide via human-to-human transmission. We aimed to describe the epidemiological and demographic features of COVID-19 outside Wuhan.
Methods: A single-center case series of 136 consecutive (from January 16 to February 17, 2020) patients with confirmed COVID-19 hospitalized in The First People's Hospital of Jingzhou, China, was retrospectively analyzed. Outcomes were followed up until February 19, 2020.
Results: Of the 136 patients (median age, 49 years; interquartile range [IQR], 33-63 years; range, 0.3-83 years), 91 (67%) had been to Wuhan or contacted persons from Wuhan. Forty-five (33.1%) were familial clusters. The median incubation period was 6 days (IQR: 4-11 days). All children had an exact exposure history, family members with COVID-19, and "Mild/Moderate" symptoms at admission. Among the 64 elderly patients, 14 (21.9%) had no exposure history, and 43 (67.2%) had a chronic illness. All 11 (8.1%) "Severe/very severe" illness at onset cases and 5 (3.7%) fatal cases were elderly patients. The duration from symptom onset to admission was positively correlated with the duration from symptom onset to endpoint. Overall, patients with a longer incubation period had more severe outcomes.
Conclusion: As high-risk susceptible groups, strong protection should be implemented for children and the elderly. Universal screening should be performed for people with a clear exposure history, even lacking apparent symptoms. Given the rapid progression of COVID-19, people should be admitted quickly following symptom onset.
Keywords: China; Coronavirus disease 2019; Epidemiology; High-risk susceptible people; Incubation period.