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J Int Med Res . Temporal lung changes in high-resolution chest computed tomography for coronavirus disease 2019

tetano

Editor, Senior Moderator
J Int Med Res


. 2020 Sep;48(9):300060520950990.
doi: 10.1177/0300060520950990.
Temporal lung changes in high-resolution chest computed tomography for coronavirus disease 2019


Chengyang Chen[SUP] 1 [/SUP], Xing Wang[SUP] 1 [/SUP], Jia Dong[SUP] 1 [/SUP], Dianer Nie[SUP] 1 [/SUP], Qianlan Chen[SUP] 1 [/SUP], Feng Yang[SUP] 1 [/SUP], Weiwei Chen[SUP] 1 [/SUP], Qiongjie Hu[SUP] 1 [/SUP]



Affiliations
Free article

Abstract

Objective: To evaluate temporal lung changes in coronavirus disease 2019 (COVID-19) in high-resolution computed tomography (HRCT) and to determine the appropriate computed tomographic (CT) follow-up time.
Methods: Eighty-six patients with two or more HRCT scans who were diagnosed with COVID-19 were included. The CT score and major CT findings were evaluated.
Results: Eighty-two (95.3%) patients had lesions on the initial HRCT scans. Most scans showed bilateral, multifocal lung lesions, with multiple lobes involved and diffuse distribution. For fifty-seven patients with type I (progress compared with the initial CT score), the CT score reached a peak at 12 days and the nadir at 36 days. For twenty-nine patients with type II (no progress compared with the initial CT score), the lowest CT score was reached at 23 days. On the final HRCT scans (>21 days), patients with a reticular pattern were older than those without a reticular pattern.
Conclusion: The appropriate follow-up time of CT scans is during the second week (approximately 12 days) and the fourth to fifth weeks (approximately 23-36 days) from the onset of illness. These times could help reduce the CT radiation dose and show timely changes in the course of the disease by CT.

Keywords: Coronavirus disease 19; computed tomography; fever; lung lesion; pneumonia; radiation dose.
 
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