tetano
Editor, Senior Moderator
J Intern Med
. 2021 Apr 27.
doi: 10.1111/joim.13284. Online ahead of print.
Half-year follow-up of patients recovering from severe COVID-19: Analysis of symptoms and their risk factors
Y F Shang[SUP] #[/SUP][SUP] 1 [/SUP], T Liu[SUP] #[/SUP][SUP] 2 3 [/SUP], J N Yu[SUP] #[/SUP][SUP] 1 [/SUP], X R Xu[SUP] 1 [/SUP], K R Zahid[SUP] 4 [/SUP], Y C Wei[SUP] 5 [/SUP], X H Wang[SUP] 2 3 [/SUP], F L Zhou[SUP] 1 [/SUP]
Affiliations
Abstract
Objectives: To understand the sequelae of COVID-19.
Methods: We followed up 1174 patients with severe coronavirus disease 2019 (COVID-19)who were recovered and discharged for 6 months.
Results: There were 175 cases with clear IgG results 6 months after discharge, of which 82 (46.9%) were IgG (+) and 16 (9.1%) were IgG (dim+). Four hundred and forty-one participants (55.4%) had some kind of sequelae. The most common symptoms were fatigue (25.3%), sleep disorder (23.2%) and shortness of breath (20.4%). In those who had sequelae, 262 (59.4%) had more than one symptom. Critical cases were more likely to have cough (20.5% vs 11.6%, p = 0.023) and hypomnesis (15.1% vs 8.0%, p = 0.041) than severe cases. Furthermore, univariate and multivariate logistic regression analyses revealed that women are more likely to have multiple symptoms (p = 0.002), fatigue (p = 0.009) and sleep disorder (p = 0.008), whereas critical illness was found as independent risk factor for hypomnesis (p = 0.045).
Conclusion: Our study demonstrated the duration of antibody and sequelae of COVID-19 and compared the differences amongst different populations.
Keywords: COVID-19; SARS-CoV-2; follow-up; symptom.
. 2021 Apr 27.
doi: 10.1111/joim.13284. Online ahead of print.
Half-year follow-up of patients recovering from severe COVID-19: Analysis of symptoms and their risk factors
Y F Shang[SUP] #[/SUP][SUP] 1 [/SUP], T Liu[SUP] #[/SUP][SUP] 2 3 [/SUP], J N Yu[SUP] #[/SUP][SUP] 1 [/SUP], X R Xu[SUP] 1 [/SUP], K R Zahid[SUP] 4 [/SUP], Y C Wei[SUP] 5 [/SUP], X H Wang[SUP] 2 3 [/SUP], F L Zhou[SUP] 1 [/SUP]
Affiliations
- PMID: 33904618
- DOI: 10.1111/joim.13284
Abstract
Objectives: To understand the sequelae of COVID-19.
Methods: We followed up 1174 patients with severe coronavirus disease 2019 (COVID-19)who were recovered and discharged for 6 months.
Results: There were 175 cases with clear IgG results 6 months after discharge, of which 82 (46.9%) were IgG (+) and 16 (9.1%) were IgG (dim+). Four hundred and forty-one participants (55.4%) had some kind of sequelae. The most common symptoms were fatigue (25.3%), sleep disorder (23.2%) and shortness of breath (20.4%). In those who had sequelae, 262 (59.4%) had more than one symptom. Critical cases were more likely to have cough (20.5% vs 11.6%, p = 0.023) and hypomnesis (15.1% vs 8.0%, p = 0.041) than severe cases. Furthermore, univariate and multivariate logistic regression analyses revealed that women are more likely to have multiple symptoms (p = 0.002), fatigue (p = 0.009) and sleep disorder (p = 0.008), whereas critical illness was found as independent risk factor for hypomnesis (p = 0.045).
Conclusion: Our study demonstrated the duration of antibody and sequelae of COVID-19 and compared the differences amongst different populations.
Keywords: COVID-19; SARS-CoV-2; follow-up; symptom.