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J Med Virol . Arrhythmia May Contribute to Neuropsychiatric Symptoms in COVID-19 Patients

tetano

Editor, Senior Moderator
J Med Virol


. 2022 Jan 8.
doi: 10.1002/jmv.27583. Online ahead of print.
Arrhythmia May Contribute to Neuropsychiatric Symptoms in COVID-19 Patients


Shu Yuan[SUP] 1 [/SUP], Si-Cong Jiang[SUP] 2 [/SUP], Zhong-Wei Zhang[SUP] 1 [/SUP], Yu-Fan Fu[SUP] 1 [/SUP], Zi-Lin Li[SUP] 3 [/SUP], Jing Hu[SUP] 4 [/SUP]



Affiliations

Abstract

Forero-Peña et al. [SUP]1[/SUP] described immediate and long-term neuropsychiatric complications following the Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, and discussed the possible roles of (hydroxy)chloroquine and dexamethasone on these neuropsychiatric symptoms… However, arrhythmia may also contribute to neuropsychiatric symptoms in COVID-19 Patients and should not be neglected. Through literature search, we summarized abnormal electrocardiographic (ECG) findings in COVID-19 patients. Sinus tachycardia was the most common arrhythmia found in the patients, with frequencies of 16.9% - 70.4% (Table 1)… Thus, anti-arrhythmic drugs, such as amiodarone and metoprolol may be used for COVID-19 patients with ventricular arrhythmia to reduce the possible complication of neuropsychiatric disorders… Chloroquine and hydroxychloroquine have been widely used in COVID-19 treatments. However, there is compelling evidence that chloroquine and hydroxychloroquine induce significant QTc prolongation and potentially increase the risk of arrhythmia… Either psychiatric symptoms or arrhythmia in COVID-19 patients undergoing steroid treatments have not been well described in the literature. This article is protected by copyright. All rights reserved.

Keywords: Blood; Epidemiology; Nervous system; Pathogenesis; SARS coronavirus; Virus classification.
 
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