tetano
Editor, Senior Moderator
J Med Virol
. 2020 Jun 10.
doi: 10.1002/jmv.26151. Online ahead of print.
Hypoalbuminaemia in COVID-19 Infection: A Predictor of Severity or a Potential Therapeutic Target?
Rahul Herlekar[SUP] 1 [/SUP], Akangsha Sur Roy[SUP] 1 [/SUP], Montgomery Matson[SUP] 1 [/SUP]
Affiliations
Abstract
We read with interest the findings of Huang's et al.'s retrospective study which revealed an association between hypoalbuminaemia and mortality in COVID-19. In response to their findings we have synthesised a structured summary of the literature in order to discuss conclusions that could be drawn collectively. Furthermore, the authors also discuss a potential therapeutic role for correction of this hypoalbuminaemia. We would like to consider the applicability and relevance of the existing literature concerning albumin infusion in acute respiratory distress syndrome (ARDS) and severe sepsis, the principal causes of mortality in COVID-19. This article is protected by copyright. All rights reserved.
Keywords: Coronavirus < Virus classification; Generalized infection < Pathogenesis; Respiratory tract < Pathogenesis.
. 2020 Jun 10.
doi: 10.1002/jmv.26151. Online ahead of print.
Hypoalbuminaemia in COVID-19 Infection: A Predictor of Severity or a Potential Therapeutic Target?
Rahul Herlekar[SUP] 1 [/SUP], Akangsha Sur Roy[SUP] 1 [/SUP], Montgomery Matson[SUP] 1 [/SUP]
Affiliations
- PMID: 32519791
- DOI: 10.1002/jmv.26151
Abstract
We read with interest the findings of Huang's et al.'s retrospective study which revealed an association between hypoalbuminaemia and mortality in COVID-19. In response to their findings we have synthesised a structured summary of the literature in order to discuss conclusions that could be drawn collectively. Furthermore, the authors also discuss a potential therapeutic role for correction of this hypoalbuminaemia. We would like to consider the applicability and relevance of the existing literature concerning albumin infusion in acute respiratory distress syndrome (ARDS) and severe sepsis, the principal causes of mortality in COVID-19. This article is protected by copyright. All rights reserved.
Keywords: Coronavirus < Virus classification; Generalized infection < Pathogenesis; Respiratory tract < Pathogenesis.