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Keeping an eye on H1N1

JimO

Well-known member
http://web.mit.edu/newsoffice/2011/h1n1-mutation-0309.html

Keeping an eye on H1N1

...In a new study from MIT, researchers have identified a single mutation in the H1N1 genetic makeup that would allow it to be much more easily transmitted between people. The finding, reported in the March 2 edition of the journal Public Library of Science (PLoS) One, should give the World Health Organization, which tracks influenza evolution, something to watch out for, says Ram Sasisekharan, senior author of the paper.

...

If such a mutant virus evolved, it could generate a ?second wave? like the ones seen in 1918 and in 1957 (known as the ?Asian flu?). ?If you look at the history, it takes a very small change to these viruses to have a dramatic effect,? Sasisekharan says.

...more at link
 
Re: Keeping an eye on H1N1

Link to the abstract of:

A Single Base-Pair Change in 2009 H1N1 Hemagglutinin Increases Human Receptor Affinity and Leads to Efficient Airborne Viral Transmission in Ferrets

by Akila Jayaraman, Claudia Pappas, Rahul Raman, Jessica A. Belser, Karthik Viswanathan, Zachary Shriver, Terrence M. Tumpey, Ram Sasisekharan

http://www.flutrackers.com/forum/showthread.php?t=163735
 
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