tetano
Editor, Senior Moderator
Mini Rev Med Chem
. 2021 Jan 4.
doi: 10.2174/1389557521666210104165733. Online ahead of print.
A mini review on emerging targets and Approaches for the synthesis of Anti-Viral compounds: In perspective to COVID-19
Maheswara Rao Gokada[SUP] 1 [/SUP], Visweswara Rao Pasupuleti[SUP] 2 [/SUP], Hari Babu Bollikolla[SUP] 1 [/SUP]
Affiliations
Abstract
The novel Coronavirus disease (COVID-19) is an epidemic disease which appeared at the end of the year 2019 in a sudden increase in number and considered as a pandemic disease caused by a viral infection and it has threatened most countries towards the emergency search for new anti-SARS-COV drugs /vaccines. At present, the number of clinical trials is ongoing worldwide on different drugs i.e. Hydroxychloroquine, Remedisvir, Favipiravir that utilizes various mechanisms of actions. A few world countries are currently processing for clinical trials which may result in a positive manner. Favipiravir (FPV) represents one of the feasible treatment options for COVID-19, if trials result seems positive. Favipiravir will be one among the developed authoritative possible drugs to warrant the benefits to mankind with large-scale production in order to meet the demands by the current pandemic Covid-19 outbreak and the future epidemic outbreaks. In this review, the authors tried to explore key molecules, which will be supportive for scheming COVID-19 research.
Keywords: COVID-19.; Coronavirus; Favipiravir; Hydroxychloroquine; Mechanism of action; Remedisvir.
. 2021 Jan 4.
doi: 10.2174/1389557521666210104165733. Online ahead of print.
A mini review on emerging targets and Approaches for the synthesis of Anti-Viral compounds: In perspective to COVID-19
Maheswara Rao Gokada[SUP] 1 [/SUP], Visweswara Rao Pasupuleti[SUP] 2 [/SUP], Hari Babu Bollikolla[SUP] 1 [/SUP]
Affiliations
- PMID: 33397236
- DOI: 10.2174/1389557521666210104165733
Abstract
The novel Coronavirus disease (COVID-19) is an epidemic disease which appeared at the end of the year 2019 in a sudden increase in number and considered as a pandemic disease caused by a viral infection and it has threatened most countries towards the emergency search for new anti-SARS-COV drugs /vaccines. At present, the number of clinical trials is ongoing worldwide on different drugs i.e. Hydroxychloroquine, Remedisvir, Favipiravir that utilizes various mechanisms of actions. A few world countries are currently processing for clinical trials which may result in a positive manner. Favipiravir (FPV) represents one of the feasible treatment options for COVID-19, if trials result seems positive. Favipiravir will be one among the developed authoritative possible drugs to warrant the benefits to mankind with large-scale production in order to meet the demands by the current pandemic Covid-19 outbreak and the future epidemic outbreaks. In this review, the authors tried to explore key molecules, which will be supportive for scheming COVID-19 research.
Keywords: COVID-19.; Coronavirus; Favipiravir; Hydroxychloroquine; Mechanism of action; Remedisvir.