tetano
Editor, Senior Moderator
Nat Commun
. 2022 Apr 5;13(1):1812.
doi: 10.1038/s41467-022-29513-z.
Course of post COVID-19 disease symptoms over time in the ComPaRe long COVID prospective e-cohort
Viet-Thi Tran[SUP] 1 2 [/SUP], Raphaël Porcher[SUP] 3 4 [/SUP], Isabelle Pane[SUP] 3 [/SUP], Philippe Ravaud[SUP] 3 4 5 [/SUP]
Affiliations
Abstract
About 10% of people infected by severe acute respiratory syndrome coronavirus 2 experience post COVID-19 disease. We analysed data from 968 adult patients (5350 person-months) with a confirmed infection enroled in the ComPaRe long COVID cohort, a disease prevalent prospective e-cohort of such patients in France. Day-by-day prevalence of post COVID-19 symptoms was determined from patients' responses to the Long COVID Symptom Tool, a validated self-reported questionnaire assessing 53 symptoms. Among patients symptomatic after 2 months, 85% still reported symptoms one year after their symptom onset. Evolution of symptoms showed a decreasing prevalence over time for 27/53 symptoms (e.g., loss of taste/smell); a stable prevalence over time for 18/53 symptoms (e.g., dyspnoea), and an increasing prevalence over time for 8/53 symptoms (e.g., paraesthesia). The disease impact on patients' lives began increasing 6 months after onset. Our results are of importance to understand the natural history of post COVID-19 disease.
. 2022 Apr 5;13(1):1812.
doi: 10.1038/s41467-022-29513-z.
Course of post COVID-19 disease symptoms over time in the ComPaRe long COVID prospective e-cohort
Viet-Thi Tran[SUP] 1 2 [/SUP], Raphaël Porcher[SUP] 3 4 [/SUP], Isabelle Pane[SUP] 3 [/SUP], Philippe Ravaud[SUP] 3 4 5 [/SUP]
Affiliations
- PMID: 35383197
- DOI: 10.1038/s41467-022-29513-z
Abstract
About 10% of people infected by severe acute respiratory syndrome coronavirus 2 experience post COVID-19 disease. We analysed data from 968 adult patients (5350 person-months) with a confirmed infection enroled in the ComPaRe long COVID cohort, a disease prevalent prospective e-cohort of such patients in France. Day-by-day prevalence of post COVID-19 symptoms was determined from patients' responses to the Long COVID Symptom Tool, a validated self-reported questionnaire assessing 53 symptoms. Among patients symptomatic after 2 months, 85% still reported symptoms one year after their symptom onset. Evolution of symptoms showed a decreasing prevalence over time for 27/53 symptoms (e.g., loss of taste/smell); a stable prevalence over time for 18/53 symptoms (e.g., dyspnoea), and an increasing prevalence over time for 8/53 symptoms (e.g., paraesthesia). The disease impact on patients' lives began increasing 6 months after onset. Our results are of importance to understand the natural history of post COVID-19 disease.