tetano
Editor, Senior Moderator
Nat Rev Microbiol
. 2020 Jun 11.
doi: 10.1038/s41579-020-0394-z. Online ahead of print.
Bat-borne Virus Diversity, Spillover and Emergence
Michael Letko[SUP] 1 2 [/SUP], Stephanie N Seifert[SUP] 3 [/SUP], Kevin J Olival[SUP] 4 [/SUP], Raina K Plowright[SUP] 5 [/SUP], Vincent J Munster[SUP] 6 [/SUP]
Affiliations
Abstract
Most viral pathogens in humans have animal origins and arose through cross-species transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus, Nipah virus, Hendra virus, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory coronavirus (MERS-CoV) and SARS-CoV-2, have been linked back to various bat species. Despite decades of research into bats and the pathogens they carry, the fields of bat virus ecology and molecular biology are still nascent, with many questions largely unexplored, thus hindering our ability to anticipate and prepare for the next viral outbreak. In this Review, we discuss the latest advancements and understanding of bat-borne viruses, reflecting on current knowledge gaps and outlining the potential routes for future research as well as for outbreak response and prevention efforts.
. 2020 Jun 11.
doi: 10.1038/s41579-020-0394-z. Online ahead of print.
Bat-borne Virus Diversity, Spillover and Emergence
Michael Letko[SUP] 1 2 [/SUP], Stephanie N Seifert[SUP] 3 [/SUP], Kevin J Olival[SUP] 4 [/SUP], Raina K Plowright[SUP] 5 [/SUP], Vincent J Munster[SUP] 6 [/SUP]
Affiliations
- PMID: 32528128
- DOI: 10.1038/s41579-020-0394-z
Abstract
Most viral pathogens in humans have animal origins and arose through cross-species transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus, Nipah virus, Hendra virus, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory coronavirus (MERS-CoV) and SARS-CoV-2, have been linked back to various bat species. Despite decades of research into bats and the pathogens they carry, the fields of bat virus ecology and molecular biology are still nascent, with many questions largely unexplored, thus hindering our ability to anticipate and prepare for the next viral outbreak. In this Review, we discuss the latest advancements and understanding of bat-borne viruses, reflecting on current knowledge gaps and outlining the potential routes for future research as well as for outbreak response and prevention efforts.