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Open Forum Infect Dis . Cohabitation With a Known Coronavirus Disease 2019 Case Is Associated With Greater Antibody Concentration and Symptom Sever

tetano

Editor, Senior Moderator
Open Forum Infect Dis


. 2021 Jul 24;8(7):ofab244.
doi: 10.1093/ofid/ofab244. eCollection 2021 Jul.
Cohabitation With a Known Coronavirus Disease 2019 Case Is Associated With Greater Antibody Concentration and Symptom Severity in a Community-Based Sample of Seropositive Adults


Joshua M Schrock[SUP] 1 2 3 [/SUP], Daniel T Ryan[SUP] 1 2 [/SUP], Rana Saber[SUP] 1 2 [/SUP], Nanette Benbow[SUP] 4 [/SUP], Lauren A Vaught[SUP] 5 6 [/SUP], Nina Reiser[SUP] 5 6 [/SUP], Matthew P Velez[SUP] 5 6 [/SUP], Ryan Hsieh[SUP] 5 6 [/SUP], Michael Newcomb[SUP] 1 2 [/SUP], Alexis R Demonbreun[SUP] 5 7 [/SUP], Brian Mustanski[SUP] 1 2 [/SUP], Elizabeth M McNally[SUP] 5 6 8 [/SUP], Richard D'Aquila[SUP] 9 [/SUP], Thomas W McDade[SUP] 3 10 [/SUP]



Affiliations

Abstract

In a community-based sample of seropositive adults (n = 1101), we found that seropositive individuals who lived with a known coronavirus disease 2019 (COVID-19) case exhibited higher blood anti-severe acute respiratory syndrome coronavirus 2 spike receptor-binding domain immunoglobulin G concentrations and greater symptom severity compared to seropositive individuals who did not live with a known COVID-19 case.

Keywords: immunity; severe acute respiratory syndrome coronavirus 2; transmission.
 
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