tetano
Editor, Senior Moderator
Pediatr Infect Dis J
. 2022 Aug 1;41(8):663-665.
doi: 10.1097/INF.0000000000003578. Epub 2022 Jul 13.
Orbito-Frontal Cortex Hypometabolism in Children With Post-COVID Condition (Long COVID): A Preliminary Experience
Fabrizio Cocciolillo[SUP] 1 [/SUP], Daniela Di Giuda[SUP] 1 2 [/SUP], Rosa Morello[SUP] 3 [/SUP], Cristina De Rose[SUP] 3 [/SUP], Piero Valentini[SUP] 3 [/SUP], Danilo Buonsenso[SUP] 3 4 [/SUP]
Affiliations
Abstract
We describe 3 children with new-onset neurocognitive problems after coronavirus disease 2019 (COVID-19), that showed, at the brain [18F]-fluorodeoxyglucose positron emission tomography/computed tomography, hypometabolism in the left orbito-frontal region. The voxel-wise analysis confirmed a cluster of hypometabolic voxels in this region with a peak at -18/46/-4mm (179 voxels, T-Score 8.1). These findings may explain neurocognitive symptoms that some children develop after COVID-19 and require further investigations.
. 2022 Aug 1;41(8):663-665.
doi: 10.1097/INF.0000000000003578. Epub 2022 Jul 13.
Orbito-Frontal Cortex Hypometabolism in Children With Post-COVID Condition (Long COVID): A Preliminary Experience
Fabrizio Cocciolillo[SUP] 1 [/SUP], Daniela Di Giuda[SUP] 1 2 [/SUP], Rosa Morello[SUP] 3 [/SUP], Cristina De Rose[SUP] 3 [/SUP], Piero Valentini[SUP] 3 [/SUP], Danilo Buonsenso[SUP] 3 4 [/SUP]
Affiliations
- PMID: 35839175
- DOI: 10.1097/INF.0000000000003578
Abstract
We describe 3 children with new-onset neurocognitive problems after coronavirus disease 2019 (COVID-19), that showed, at the brain [18F]-fluorodeoxyglucose positron emission tomography/computed tomography, hypometabolism in the left orbito-frontal region. The voxel-wise analysis confirmed a cluster of hypometabolic voxels in this region with a peak at -18/46/-4mm (179 voxels, T-Score 8.1). These findings may explain neurocognitive symptoms that some children develop after COVID-19 and require further investigations.