tetano
Editor, Senior Moderator
Citation: Verger P, Flicoteaux R, Schwarzinger M, Sagaon-Teyssier L, Peretti-Watel P, et al. (2012) Pandemic Influenza (A/H1N1) Vaccine Uptake among French Private General Practitioners: A Cross Sectional Study in 2010. PLoS ONE 7(8): e41837. doi:10.1371/journal.pone.0041837
Pierre Verger1,2,3*, R?mi Flicoteaux4, Michael Schwarzinger5,6, Luis Sagaon-Teyssier1,2,3, Patrick Peretti-Watel1,2,3, Odile Launay7, Remy Sebbah8, Jean-Paul Moatti1,2,3
1 U912 Sciences Economiques & Sociales de la Sant? & Traitement de l?Information M?dicale, Institut National de la Sant? et de la Recherche M?dicale, Marseilles, France, 2 UMR-S912, Aix Marseille Universit?, Institut Recherche et D?veloppement, Marseilles, France, 3 Observatoire R?gional de la Sant? Provence-Alpes-C?te d'Azur, Marseilles, France, 4 D?partement de Biostatistique et d'Information M?dicale, H?pital Saint Louis, Assistance Publique des H?pitaux de Paris, Paris, France, 5 U738 Action Th?matique et Incitative sur Programme-AVENIR, Institut National de la Sant? et de la Recherche M?dicale, Paris, France, 6 UMR-S738, Universit? Paris Diderot, Sorbonne Paris Cit?, Paris, France, 7 Centre d?Investigations Cliniques BT505, Institut National de la Sant? et de la Recherche M?dicale, Paris, France, 8 Union r?gionale des professionnels de sant?, m?decins lib?raux, Provence-Alpes-C?te d'Azur, Marseilles, France
Abstract Top
Background
In July, 2009, French health authorities, like those in many other countries, decided to embark on a mass vaccination campaign against the pandemic A(H1N1) influenza. Private general practitioners (GPs) were not involved in this campaign. We studied GPs? pandemic vaccine (pvaccine) uptake, quantified the relative contribution of its potential explanatory factors and studied whether their own vaccination choice was correlated with their recommendations to patients about pvaccination.
Methodology/Principal Findings
In this cross-sectional telephone survey, professional investigators interviewed an existing panel of randomly selected private GPs (N = 1431; response rate at inclusion in the panel: 36.8%; participation rate in the survey: 100%). The main outcome variable was GPs? own pvaccine uptake. We used an averaging multi-model approach to quantify the relative contribution of factors associated with their vaccination. The pvaccine uptake rate was 61% (95%CI = 58.3?63.3). Four independent factors contributed the most to this rate (partial Nagelkerke?s R2): history of previous vaccination against seasonal influenza (14.5%), perception of risks and efficacy of the pvaccine (10.8%), opinions regarding the organization of the vaccination campaign (7.1%), and perception of the pandemic's severity (5.2%). Overall, 71.3% (95%CI = 69.0?73.6) of the participants recommended pvaccination to young adults at risk and 40.1% (95%CI = 37.6?42.7) to other young adults. GPs? own pvaccination was strongly predictive of their recommendation to both young adults at risk (OR = 9.6; 95%CI = 7.2?12.6) and those not at risk (OR = 8.5; 95%CI = 6.4?11.4).
Conclusions/Significance
These results suggest that around 60% of French private GPs followed French authorities? recommendations about vaccination of health care professionals against the A(H1N1) influenza. They pinpoint priority levers for improving preparedness for future influenza pandemics. Besides encouraging GPs' own uptake of regular vaccination against seasonal influenza, providing GPs with clear information about the risks and efficacy of any new pvaccine and involving them in the organization of any future vaccine campaign may improve their pvaccine uptake.
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0041837
Pierre Verger1,2,3*, R?mi Flicoteaux4, Michael Schwarzinger5,6, Luis Sagaon-Teyssier1,2,3, Patrick Peretti-Watel1,2,3, Odile Launay7, Remy Sebbah8, Jean-Paul Moatti1,2,3
1 U912 Sciences Economiques & Sociales de la Sant? & Traitement de l?Information M?dicale, Institut National de la Sant? et de la Recherche M?dicale, Marseilles, France, 2 UMR-S912, Aix Marseille Universit?, Institut Recherche et D?veloppement, Marseilles, France, 3 Observatoire R?gional de la Sant? Provence-Alpes-C?te d'Azur, Marseilles, France, 4 D?partement de Biostatistique et d'Information M?dicale, H?pital Saint Louis, Assistance Publique des H?pitaux de Paris, Paris, France, 5 U738 Action Th?matique et Incitative sur Programme-AVENIR, Institut National de la Sant? et de la Recherche M?dicale, Paris, France, 6 UMR-S738, Universit? Paris Diderot, Sorbonne Paris Cit?, Paris, France, 7 Centre d?Investigations Cliniques BT505, Institut National de la Sant? et de la Recherche M?dicale, Paris, France, 8 Union r?gionale des professionnels de sant?, m?decins lib?raux, Provence-Alpes-C?te d'Azur, Marseilles, France
Abstract Top
Background
In July, 2009, French health authorities, like those in many other countries, decided to embark on a mass vaccination campaign against the pandemic A(H1N1) influenza. Private general practitioners (GPs) were not involved in this campaign. We studied GPs? pandemic vaccine (pvaccine) uptake, quantified the relative contribution of its potential explanatory factors and studied whether their own vaccination choice was correlated with their recommendations to patients about pvaccination.
Methodology/Principal Findings
In this cross-sectional telephone survey, professional investigators interviewed an existing panel of randomly selected private GPs (N = 1431; response rate at inclusion in the panel: 36.8%; participation rate in the survey: 100%). The main outcome variable was GPs? own pvaccine uptake. We used an averaging multi-model approach to quantify the relative contribution of factors associated with their vaccination. The pvaccine uptake rate was 61% (95%CI = 58.3?63.3). Four independent factors contributed the most to this rate (partial Nagelkerke?s R2): history of previous vaccination against seasonal influenza (14.5%), perception of risks and efficacy of the pvaccine (10.8%), opinions regarding the organization of the vaccination campaign (7.1%), and perception of the pandemic's severity (5.2%). Overall, 71.3% (95%CI = 69.0?73.6) of the participants recommended pvaccination to young adults at risk and 40.1% (95%CI = 37.6?42.7) to other young adults. GPs? own pvaccination was strongly predictive of their recommendation to both young adults at risk (OR = 9.6; 95%CI = 7.2?12.6) and those not at risk (OR = 8.5; 95%CI = 6.4?11.4).
Conclusions/Significance
These results suggest that around 60% of French private GPs followed French authorities? recommendations about vaccination of health care professionals against the A(H1N1) influenza. They pinpoint priority levers for improving preparedness for future influenza pandemics. Besides encouraging GPs' own uptake of regular vaccination against seasonal influenza, providing GPs with clear information about the risks and efficacy of any new pvaccine and involving them in the organization of any future vaccine campaign may improve their pvaccine uptake.
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0041837