tetano
Editor, Senior Moderator
Vaccine. 2010 Jun 9. [Epub ahead of print]
Protection of trivalent inactivated influenza vaccine against hospitalizations among pandemic influenza A (H1N1) cases in Argentina.
Orellano PW, Reynoso JI, Carlino O, Uez O.
Departamento de Epidemiolog?a, Ministerio de Salud de Tierra del Fuego, Leopoldo Lugones s/n Casa 8, Ushuaia, Tierra del Fuego 9410, Argentina.
Abstract
The aim of this study was to estimate the effectiveness of 2009 seasonal trivalent inactivated vaccine in reducing hospitalizations due to the novel influenza A H1N1 virus among positive cases. Data collected from Argentina's national epidemiological surveillance system were analyzed. All patients had a clinical diagnosis and underwent positive serological tests for pandemic influenza A H1N1. Logistic regression was used to estimate vaccine effectiveness to prevent severe cases of the disease, measured as hospitalizations. The adjusted effectiveness of the vaccine was 50% (95% CI: 40-59%). Vaccination was significantly associated with hospitalizations in all age groups, and within groups that had and had not received antiviral treatment. These results suggest that seasonal influenza vaccine might have conferred partial protection against severe cases due to the novel pandemic influenza. Copyright ? 2010 Elsevier Ltd. All rights reserved.
PMID: 20541580 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20541580
Protection of trivalent inactivated influenza vaccine against hospitalizations among pandemic influenza A (H1N1) cases in Argentina.
Orellano PW, Reynoso JI, Carlino O, Uez O.
Departamento de Epidemiolog?a, Ministerio de Salud de Tierra del Fuego, Leopoldo Lugones s/n Casa 8, Ushuaia, Tierra del Fuego 9410, Argentina.
Abstract
The aim of this study was to estimate the effectiveness of 2009 seasonal trivalent inactivated vaccine in reducing hospitalizations due to the novel influenza A H1N1 virus among positive cases. Data collected from Argentina's national epidemiological surveillance system were analyzed. All patients had a clinical diagnosis and underwent positive serological tests for pandemic influenza A H1N1. Logistic regression was used to estimate vaccine effectiveness to prevent severe cases of the disease, measured as hospitalizations. The adjusted effectiveness of the vaccine was 50% (95% CI: 40-59%). Vaccination was significantly associated with hospitalizations in all age groups, and within groups that had and had not received antiviral treatment. These results suggest that seasonal influenza vaccine might have conferred partial protection against severe cases due to the novel pandemic influenza. Copyright ? 2010 Elsevier Ltd. All rights reserved.
PMID: 20541580 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20541580