tetano
Editor, Senior Moderator
Radiol Case Rep
. 2022 Oct 13;17(12):4879-4884.
doi: 10.1016/j.radcr.2022.08.017. eCollection 2022 Dec.
Multiple ischemic stroke with pulmonary embolism revealing severe COVID-19 infection in a young healthy patient
Hicham Benramdane[SUP] 1 2 [/SUP], Siham Nasri[SUP] 1 2 [/SUP], Nada Ouahabi[SUP] 1 3 [/SUP], Aahd Belharti[SUP] 1 2 [/SUP], Kaouthar Chehita[SUP] 1 4 [/SUP], Mebrouk Yassine[SUP] 1 4 [/SUP], Brahim Housni[SUP] 1 3 [/SUP], Imane Skiker[SUP] 1 2 [/SUP]
Affiliations
Abstract
Coronavirus 2019 (COVID-19) disease has caused significant morbidity and mortality worldwide since its emergence in December 2019. Despite its respiratory tropism; there is a nontrivial relationship between this virus and the neurovascular system exposing patients to higher morbidity and mortality. We report the case of a young patient admitted for hemiplegia with acute respiratory failure, in whom imaging found multiple ischemic strokes with pulmonary embolism and severe involvement suggestive of COVID-19 pneumopathy. Stroke in the context of COVID-19 infection has distinct characteristics in terms of disease mechanism, patient demographics, but also clinical, biological, and neuroradiological specificities. The pathogenesis and optimal management of COVID-19-associated ischemic stroke remain unclear, but the coagulopathy and endotheliopathy triggered by the cytokine storm represent possible target mechanisms.
Keywords: COVID-19; Coagulopathy; Ischemic stroke; Neuroinflammation.
. 2022 Oct 13;17(12):4879-4884.
doi: 10.1016/j.radcr.2022.08.017. eCollection 2022 Dec.
Multiple ischemic stroke with pulmonary embolism revealing severe COVID-19 infection in a young healthy patient
Hicham Benramdane[SUP] 1 2 [/SUP], Siham Nasri[SUP] 1 2 [/SUP], Nada Ouahabi[SUP] 1 3 [/SUP], Aahd Belharti[SUP] 1 2 [/SUP], Kaouthar Chehita[SUP] 1 4 [/SUP], Mebrouk Yassine[SUP] 1 4 [/SUP], Brahim Housni[SUP] 1 3 [/SUP], Imane Skiker[SUP] 1 2 [/SUP]
Affiliations
- PMID: 36247700
- PMCID: PMC9557746
- DOI: 10.1016/j.radcr.2022.08.017
Abstract
Coronavirus 2019 (COVID-19) disease has caused significant morbidity and mortality worldwide since its emergence in December 2019. Despite its respiratory tropism; there is a nontrivial relationship between this virus and the neurovascular system exposing patients to higher morbidity and mortality. We report the case of a young patient admitted for hemiplegia with acute respiratory failure, in whom imaging found multiple ischemic strokes with pulmonary embolism and severe involvement suggestive of COVID-19 pneumopathy. Stroke in the context of COVID-19 infection has distinct characteristics in terms of disease mechanism, patient demographics, but also clinical, biological, and neuroradiological specificities. The pathogenesis and optimal management of COVID-19-associated ischemic stroke remain unclear, but the coagulopathy and endotheliopathy triggered by the cytokine storm represent possible target mechanisms.
Keywords: COVID-19; Coagulopathy; Ischemic stroke; Neuroinflammation.