tetano
Editor, Senior Moderator
Respir Physiol Neurobiol
. 2020 Jul 14;103494.
doi: 10.1016/j.resp.2020.103494. Online ahead of print.
High altitude reduces infection rate of COVID-19 but not case-fatality rate
Jose Segovia-Juarez[SUP] 1 [/SUP], Jes?s M Castagnetto[SUP] 2 [/SUP], Gustavo F Gonzales[SUP] 3 [/SUP]
Affiliations
Abstract
Coronavirus disease 19 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is suggested that life at high altitude may reduce COVID infections and case-fatality rates (cases/deaths). We study data from Peru COVID-19 pandemics, which first case was recorded on March 6th, 2020. By June 13, 2020 there were 6498 deaths, and 224,132 SARS-CoV-2 positives. Using data from 185 capitals of provinces with altitudes ranging from 3 to 4342 m, we confirm previous reports that infection with COVID-19 at high altitude is reduced. However, case-fatality rate is not dependent of altitude. We have also presented first evidence that female protection towards death by COVID-19 is reduced as altitude of residence increases.
Keywords: Altitude; COVID-19; Fatality rate; Hypoxia.
. 2020 Jul 14;103494.
doi: 10.1016/j.resp.2020.103494. Online ahead of print.
High altitude reduces infection rate of COVID-19 but not case-fatality rate
Jose Segovia-Juarez[SUP] 1 [/SUP], Jes?s M Castagnetto[SUP] 2 [/SUP], Gustavo F Gonzales[SUP] 3 [/SUP]
Affiliations
- PMID: 32679369
- PMCID: PMC7361094
- DOI: 10.1016/j.resp.2020.103494
Abstract
Coronavirus disease 19 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is suggested that life at high altitude may reduce COVID infections and case-fatality rates (cases/deaths). We study data from Peru COVID-19 pandemics, which first case was recorded on March 6th, 2020. By June 13, 2020 there were 6498 deaths, and 224,132 SARS-CoV-2 positives. Using data from 185 capitals of provinces with altitudes ranging from 3 to 4342 m, we confirm previous reports that infection with COVID-19 at high altitude is reduced. However, case-fatality rate is not dependent of altitude. We have also presented first evidence that female protection towards death by COVID-19 is reduced as altitude of residence increases.
Keywords: Altitude; COVID-19; Fatality rate; Hypoxia.