tetano
Editor, Senior Moderator
Respirol Case Rep
. 2022 Jun 7;10(7):e0979.
doi: 10.1002/rcr2.979. eCollection 2022 Jul.
A case report of coronavirus disease-2019-induced acute asthma exacerbation in an obese patient
Hisashi Sasaki[SUP] 1 2 [/SUP], Jun Miyata[SUP] 2 [/SUP], Ai Kobayashi[SUP] 1 [/SUP], Shuichi Kawano[SUP] 1 [/SUP], Akihiko Kawana[SUP] 2 [/SUP]
Affiliations
Abstract
The coronavirus disease-2019 (COVID-19) has spread worldwide. Previous studies indicated a low prevalence of COVID-19 induced acute exacerbations of asthma. We present a 39-year-old-male obese asthmatic case who experienced acute asthma exacerbation during COVID-19. On day 8 of infection, his cough and dyspnea worsened with hypoxia and wheezing. Laboratory test results revealed elevated interleukin-6 (IL-6) and total immunoglobulin E (IgE) levels without eosinophilia. Two months since the onset, hypoxia disappeared with decreased IL-6 and IgE levels. Our case suggested that obesity and high serum IL-6 and IgE levels may have contributed to atypical asthma exacerbation in COVID-19.
Keywords: COVID‐19; asthma; immunoglobulin E; interleukin‐6; obesity.
. 2022 Jun 7;10(7):e0979.
doi: 10.1002/rcr2.979. eCollection 2022 Jul.
A case report of coronavirus disease-2019-induced acute asthma exacerbation in an obese patient
Hisashi Sasaki[SUP] 1 2 [/SUP], Jun Miyata[SUP] 2 [/SUP], Ai Kobayashi[SUP] 1 [/SUP], Shuichi Kawano[SUP] 1 [/SUP], Akihiko Kawana[SUP] 2 [/SUP]
Affiliations
- PMID: 35685850
- PMCID: PMC9171688
- DOI: 10.1002/rcr2.979
Abstract
The coronavirus disease-2019 (COVID-19) has spread worldwide. Previous studies indicated a low prevalence of COVID-19 induced acute exacerbations of asthma. We present a 39-year-old-male obese asthmatic case who experienced acute asthma exacerbation during COVID-19. On day 8 of infection, his cough and dyspnea worsened with hypoxia and wheezing. Laboratory test results revealed elevated interleukin-6 (IL-6) and total immunoglobulin E (IgE) levels without eosinophilia. Two months since the onset, hypoxia disappeared with decreased IL-6 and IgE levels. Our case suggested that obesity and high serum IL-6 and IgE levels may have contributed to atypical asthma exacerbation in COVID-19.
Keywords: COVID‐19; asthma; immunoglobulin E; interleukin‐6; obesity.