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SAGE Open Med Case Rep . Case report of meningoencephalitis associated with SARS-CoV-2 infection showing a decrease in idiopathic focal cerebral bl

tetano

Editor, Senior Moderator
SAGE Open Med Case Rep


. 2024 Jul 26:12:2050313X241267082.
doi: 10.1177/2050313X241267082. eCollection 2024. Case report of meningoencephalitis associated with SARS-CoV-2 infection showing a decrease in idiopathic focal cerebral blood flow

Kazumasa Sekiguchi[SUP] 1 [/SUP], Kosuke Matsuzono[SUP] 1 [/SUP], Takafumi Mashiko[SUP] 1 [/SUP], Reiji Koide[SUP] 1 [/SUP], Shigeru Fujimoto[SUP] 1 [/SUP]



Affiliations
Abstract

Some neurological complications are associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A 74-year-old man was diagnosed with infection by SARS-CoV-2. Eighteen days after SARS-CoV-2 infection, he developed disturbed consciousness and aseptic meningoencephalitis. An analysis of cerebrospinal flood revealed an elevated cell count (184/μL) and protein level (260 mg/dL). Cranial magnetic resonance imaging showed no abnormalities. By contrast, [SUP]123[/SUP]I-N-isopropyl-p-iodoamphetamine single-photon emission computed tomography showed a significant decrease in cerebral blood flow (CBF) in the left parietal and occipital lobes. He died suddenly 3 months after being transferred to a rehabilitation clinic without any clear cause of death. The SARS-CoV-2 infection can cause aseptic meningoencephalitis with a distinctive decrease in CBF pattern without magnetic resonance image abnormality or intracranial artery stenosis.

Keywords: COVID-19; SARS-CoV-2; cerebral blood flow; infection; meningoencephalitis.

 
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