tetano
Editor, Senior Moderator
Sci Rep
. 2025 Jan 2;15(1):445.
doi: 10.1038/s41598-024-84983-z. Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic
Giuseppe Nasso[SUP] #[/SUP][SUP] 1 [/SUP], Ignazio Condello[SUP] 2 3 [/SUP], Walter Vignaroli[SUP] #[/SUP][SUP] 4 [/SUP], Andrea Antonazzo[SUP] 5 [/SUP], Francesco Bartolomucci[SUP] 6 [/SUP], Barbara Pala[SUP] 7 [/SUP], Claudio Larosa[SUP] 6 [/SUP], Annachiara Pingitore[SUP] 8 [/SUP], Vincenzo Amodeo[SUP] 9 [/SUP], Vincenzo Montemurro[SUP] 10 [/SUP], Mizar D'Abramo[SUP] 11 [/SUP], Roberto Ceravolo[SUP] 12 [/SUP], Domenica Donato[SUP] 5 [/SUP], Pasquale Fratto[SUP] 5 [/SUP], Maria Grazia De Rosis[SUP] 13 [/SUP], Giuseppe Diaferia[SUP] 14 [/SUP], Rita Torraco[SUP] 14 [/SUP], Gaetano Contegiacomo[SUP] 1 [/SUP], Guido Lembo[SUP] 1 [/SUP], Mario Siro Brigiani[SUP] 1 [/SUP], Giuseppe Santarpino[SUP] 1 [/SUP], Giuseppe Speziale[SUP] 1 [/SUP]
Affiliations
Ventricular septal defect (VSD) is a serious complication of myocardial infarction (MI), with its global incidence significantly reduced in recent years due to advances in coronary reperfusion techniques. However, during the COVID-19 pandemic, there was an unexpected rise in the incidence of post-MI VSD, likely driven by delays in seeking treatment. This study retrospectively analyzed 10 cases of post-MI VSD treated at our hospitals from March 2018 to August 2023, comparing incidence rates across pre-pandemic, pandemic, and post-pandemic periods. The findings revealed a notable increase in VSD cases during the pandemic, with six cases occurring in two years, compared to only two cases in each of the pre-pandemic and post-pandemic periods. Despite these fluctuations, surgical intervention remained a crucial and effective treatment, with 60% of patients surviving the 30-day follow-up. The study underscores the impact of delayed treatment on VSD incidence during the pandemic and highlights the critical need for timely medical intervention to manage severe MI complications effectively.
Keywords: COVID-19 pandemic; Delayed treatment; Myocardial infarction; Post-MI complications; Surgical correction; Ventricular Setpal defect.
. 2025 Jan 2;15(1):445.
doi: 10.1038/s41598-024-84983-z. Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic
Giuseppe Nasso[SUP] #[/SUP][SUP] 1 [/SUP], Ignazio Condello[SUP] 2 3 [/SUP], Walter Vignaroli[SUP] #[/SUP][SUP] 4 [/SUP], Andrea Antonazzo[SUP] 5 [/SUP], Francesco Bartolomucci[SUP] 6 [/SUP], Barbara Pala[SUP] 7 [/SUP], Claudio Larosa[SUP] 6 [/SUP], Annachiara Pingitore[SUP] 8 [/SUP], Vincenzo Amodeo[SUP] 9 [/SUP], Vincenzo Montemurro[SUP] 10 [/SUP], Mizar D'Abramo[SUP] 11 [/SUP], Roberto Ceravolo[SUP] 12 [/SUP], Domenica Donato[SUP] 5 [/SUP], Pasquale Fratto[SUP] 5 [/SUP], Maria Grazia De Rosis[SUP] 13 [/SUP], Giuseppe Diaferia[SUP] 14 [/SUP], Rita Torraco[SUP] 14 [/SUP], Gaetano Contegiacomo[SUP] 1 [/SUP], Guido Lembo[SUP] 1 [/SUP], Mario Siro Brigiani[SUP] 1 [/SUP], Giuseppe Santarpino[SUP] 1 [/SUP], Giuseppe Speziale[SUP] 1 [/SUP]
Affiliations
- PMID: 39747983
- PMCID: PMC11695627
- DOI: 10.1038/s41598-024-84983-z
Ventricular septal defect (VSD) is a serious complication of myocardial infarction (MI), with its global incidence significantly reduced in recent years due to advances in coronary reperfusion techniques. However, during the COVID-19 pandemic, there was an unexpected rise in the incidence of post-MI VSD, likely driven by delays in seeking treatment. This study retrospectively analyzed 10 cases of post-MI VSD treated at our hospitals from March 2018 to August 2023, comparing incidence rates across pre-pandemic, pandemic, and post-pandemic periods. The findings revealed a notable increase in VSD cases during the pandemic, with six cases occurring in two years, compared to only two cases in each of the pre-pandemic and post-pandemic periods. Despite these fluctuations, surgical intervention remained a crucial and effective treatment, with 60% of patients surviving the 30-day follow-up. The study underscores the impact of delayed treatment on VSD incidence during the pandemic and highlights the critical need for timely medical intervention to manage severe MI complications effectively.
Keywords: COVID-19 pandemic; Delayed treatment; Myocardial infarction; Post-MI complications; Surgical correction; Ventricular Setpal defect.