tetano
Editor, Senior Moderator
Sci Total Environ. 2020 May 12;733:139358. doi: 10.1016/j.scitotenv.2020.139358. [Epub ahead of print]
Spillover of SARS-CoV-2 into novel wild hosts in North America: A conceptual model for perpetuation of the pathogen.
Franklin AB[SUP]1[/SUP], Bevins SN[SUP]2[/SUP].
Author information
Abstract
There is evidence that the current outbreak of the novel coronavirus SARS-CoV-2, which causes COVID-19, is of animal origin. As with a number of zoonotic pathogens, there is a risk of spillover into novel hosts. Here, we propose a hypothesized conceptual model that illustrates the mechanism whereby the SARS-CoV-2 could spillover from infected humans to naive wildlife hosts in North America. This proposed model is premised on transmission of SARS-CoV-2 from human feces through municipal waste water treatment plants into the natural aquatic environment where potential wildlife hosts become infected. We use the existing literature on human coronaviruses, including SARS CoV, to support the potential pathways and mechanisms in the conceptual model. Although we focus on North America, our conceptual model could apply to other parts of the globe as well.
Published by Elsevier B.V.
KEYWORDS:
Bats; COVID-19; Raccoons; Sewage; Spillback; Waste water treatment plants
PMID:32416535DOI:10.1016/j.scitotenv.2020.139358
Spillover of SARS-CoV-2 into novel wild hosts in North America: A conceptual model for perpetuation of the pathogen.
Franklin AB[SUP]1[/SUP], Bevins SN[SUP]2[/SUP].
Author information
Abstract
There is evidence that the current outbreak of the novel coronavirus SARS-CoV-2, which causes COVID-19, is of animal origin. As with a number of zoonotic pathogens, there is a risk of spillover into novel hosts. Here, we propose a hypothesized conceptual model that illustrates the mechanism whereby the SARS-CoV-2 could spillover from infected humans to naive wildlife hosts in North America. This proposed model is premised on transmission of SARS-CoV-2 from human feces through municipal waste water treatment plants into the natural aquatic environment where potential wildlife hosts become infected. We use the existing literature on human coronaviruses, including SARS CoV, to support the potential pathways and mechanisms in the conceptual model. Although we focus on North America, our conceptual model could apply to other parts of the globe as well.
Published by Elsevier B.V.
KEYWORDS:
Bats; COVID-19; Raccoons; Sewage; Spillback; Waste water treatment plants
PMID:32416535DOI:10.1016/j.scitotenv.2020.139358