tetano
Editor, Senior Moderator
J Pediatr. 2012 Aug 3. [Epub ahead of print]
Second-Hand Tobacco Smoke Exposure and Severity of Influenza in Hospitalized Children.
Wilson KM, Pier JC, Wesgate SC, Cohen JM, Blumkin AK.
Source
Children's Hospital Colorado, Aurora, CO; American Academy of Pediatrics Julius B. Richmond Center, Elk Grove Village, IL.
Abstract
OBJECTIVE:
To assess whether children with influenza who are exposed to secondhand tobacco smoke (SHS) would have more severe illness than those not exposed.
STUDY DESIGN:
We abstracted charts from pediatric inpatients with confirmed influenza from 2002-2009 for demographics, medical history, and smoke exposure. Severity indicators included intensive care, intubation, and length of stay (LOS) in the hospital; potential confounding factors included demographics and the presence of asthma or chronic conditions. All χ(2), t tests, and regression analyses were run using SPSS v. 18.0.
RESULTS:
Of 117 children, 40% were exposed to SHS, who had increased need for intensive care (30% vs 10%, P < .01) and intubation (13% vs 1%, P < .05), and had longer LOS (4.0 vs 2.4 days, P < .01). Children with chronic conditions and SHS exposure required more intensive care (53% vs 18%, P < .05) and had longer LOS (10.0 vs 3.5 days, P < .01) than children not exposed to SHS with chronic conditions. In multivariate analyses controlling for potential confounding factors, children with SHS exposure were 4.7 times more likely to be admitted to intensive care (95% CI 1.4-18.5) and had a 70% longer LOS (95% CI 12%-230%).
CONCLUSIONS:
Children with SHS exposure who are hospitalized with influenza have more severe illness. Efforts are needed to immunize this population against influenza, and eliminate children's exposure to SHS.
Copyright ? 2012 Mosby, Inc. All rights reserved.
PMID:
22863259
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22863259
Second-Hand Tobacco Smoke Exposure and Severity of Influenza in Hospitalized Children.
Wilson KM, Pier JC, Wesgate SC, Cohen JM, Blumkin AK.
Source
Children's Hospital Colorado, Aurora, CO; American Academy of Pediatrics Julius B. Richmond Center, Elk Grove Village, IL.
Abstract
OBJECTIVE:
To assess whether children with influenza who are exposed to secondhand tobacco smoke (SHS) would have more severe illness than those not exposed.
STUDY DESIGN:
We abstracted charts from pediatric inpatients with confirmed influenza from 2002-2009 for demographics, medical history, and smoke exposure. Severity indicators included intensive care, intubation, and length of stay (LOS) in the hospital; potential confounding factors included demographics and the presence of asthma or chronic conditions. All χ(2), t tests, and regression analyses were run using SPSS v. 18.0.
RESULTS:
Of 117 children, 40% were exposed to SHS, who had increased need for intensive care (30% vs 10%, P < .01) and intubation (13% vs 1%, P < .05), and had longer LOS (4.0 vs 2.4 days, P < .01). Children with chronic conditions and SHS exposure required more intensive care (53% vs 18%, P < .05) and had longer LOS (10.0 vs 3.5 days, P < .01) than children not exposed to SHS with chronic conditions. In multivariate analyses controlling for potential confounding factors, children with SHS exposure were 4.7 times more likely to be admitted to intensive care (95% CI 1.4-18.5) and had a 70% longer LOS (95% CI 12%-230%).
CONCLUSIONS:
Children with SHS exposure who are hospitalized with influenza have more severe illness. Efforts are needed to immunize this population against influenza, and eliminate children's exposure to SHS.
Copyright ? 2012 Mosby, Inc. All rights reserved.
PMID:
22863259
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22863259