tetano
Editor, Senior Moderator
J Dairy Sci. 2014 Jul 11. pii: S0022-0302(14)00492-5. doi: 10.3168/jds.2014-8016. [Epub ahead of print]
Short communication: Antiviral activity of subcritical water extract of Brassica juncea against influenza virus A/H1N1 in nonfat milk.
Lee NK1, Lee JH1, Lim SM1, Lee KA1, Kim YB2, Chang PS3, Paik HD4.
Author information
Abstract
Subcritical water extract (SWE) of Brassica juncea was studied for antiviral effects against influenza virus A/H1N1 and for the possibility of application as a nonfat milk supplement for use as an "antiviral food." At maximum nontoxic concentrations, SWE had higher antiviral activity against influenza virus A/H1N1 than n-hexane, ethanol, or hot water (80?C) extracts. Addition of 0.5 mg/mL of B. juncea SWE to culture medium led to 50.35% cell viability (% antiviral activity) for Madin-Darby canine kidney cells infected with influenza virus A/H1N1. Nonfat milk supplemented with 0.28 mg/mL of B. juncea SWE showed 39.62% antiviral activity against influenza virus A/H1N1. Thus, the use of B. juncea SWE as a food supplement might aid in protection from influenza viral infection.
Copyright ? 2014 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.
KEYWORDS:
Brassica juncea; antiviral activity; influenza virus; subcritical water extraction
PMID:
25022686
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25022686
Short communication: Antiviral activity of subcritical water extract of Brassica juncea against influenza virus A/H1N1 in nonfat milk.
Lee NK1, Lee JH1, Lim SM1, Lee KA1, Kim YB2, Chang PS3, Paik HD4.
Author information
Abstract
Subcritical water extract (SWE) of Brassica juncea was studied for antiviral effects against influenza virus A/H1N1 and for the possibility of application as a nonfat milk supplement for use as an "antiviral food." At maximum nontoxic concentrations, SWE had higher antiviral activity against influenza virus A/H1N1 than n-hexane, ethanol, or hot water (80?C) extracts. Addition of 0.5 mg/mL of B. juncea SWE to culture medium led to 50.35% cell viability (% antiviral activity) for Madin-Darby canine kidney cells infected with influenza virus A/H1N1. Nonfat milk supplemented with 0.28 mg/mL of B. juncea SWE showed 39.62% antiviral activity against influenza virus A/H1N1. Thus, the use of B. juncea SWE as a food supplement might aid in protection from influenza viral infection.
Copyright ? 2014 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.
KEYWORDS:
Brassica juncea; antiviral activity; influenza virus; subcritical water extraction
PMID:
25022686
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25022686