sharon sanders
Editor-in-Chief & President
[h=1]False positive dengue NS1 antigen test in a traveller with an acute Zika virus infection imported into Switzerland[/h] Danielle Gyurecha, Julian Schillinga, Jonas Schmidt-Chanasitb, c, Pascal Cassinottid, Franz Kaeppelid, Marinko Dobecd
a Travel Clinic, Zurich, Switzerland
b Bernhard Nocht Institute for Tropical Medicine/World Health Organization Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research, Hamburg, Germany
c German Centre for Infection Research (DZIF), Hamburg-L?beck-Borstel, Hamburg, Germany
d medica, medizinische Laboratorien Dr. F. Kaeppeli, Zurich, Switzerland
snip
The clinical presentation of Zika virus infection is usually not specific (mild fever, rash, arthralgia, and conjunctivitis) and can be confused with other diseases, especially dengue fever and chikungunya fever [15]. As no specific treatment of Zika virus infection is available and there is no vaccine or preventive drug, the treatment is symptomatic and mainly based on pain relief, fever reduction and anti-histamines for pruritic rash. Travel-related cases of Zika virus infection in patients returning from affected areas are likely to occur in the future and clinical cases suspected of dengue virus or chikungunya virus infection should be additionally tested for Zika virus. This case illustrates the urgent medical need for a broadly available assay capable of differentiating Zika from Dengue infections.
http://www.smw.ch/content/smw-2016-14296/
a Travel Clinic, Zurich, Switzerland
b Bernhard Nocht Institute for Tropical Medicine/World Health Organization Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research, Hamburg, Germany
c German Centre for Infection Research (DZIF), Hamburg-L?beck-Borstel, Hamburg, Germany
d medica, medizinische Laboratorien Dr. F. Kaeppeli, Zurich, Switzerland
snip
The clinical presentation of Zika virus infection is usually not specific (mild fever, rash, arthralgia, and conjunctivitis) and can be confused with other diseases, especially dengue fever and chikungunya fever [15]. As no specific treatment of Zika virus infection is available and there is no vaccine or preventive drug, the treatment is symptomatic and mainly based on pain relief, fever reduction and anti-histamines for pruritic rash. Travel-related cases of Zika virus infection in patients returning from affected areas are likely to occur in the future and clinical cases suspected of dengue virus or chikungunya virus infection should be additionally tested for Zika virus. This case illustrates the urgent medical need for a broadly available assay capable of differentiating Zika from Dengue infections.
http://www.smw.ch/content/smw-2016-14296/