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Systemic Allergic Contact Dermatitis After Formaldehyde-Containing Influenza Vaccination

tetano

Editor, Senior Moderator
J Cutan Med Surg. 2015 Apr 15. pii: 1203475415582306. [Epub ahead of print]
[h=1]Systemic Allergic Contact Dermatitis After Formaldehyde-Containing Influenza Vaccination.[/h] Kuritzky LA[SUP]1[/SUP], Pratt M[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Systemic contact dermatitis occurs when a patient sensitized to an allergen topically is systemically reexposed to the allergen and develops a cutaneous eruption.
[h=4]OBJECTIVE:[/h] To report the case of a 48-year-old male who developed explosive dermatitis following injection of a formaldehyde-containing influenza vaccine and was subsequently shown to be strongly positive to formaldehyde and formaldehyde-releasing allergens by patch testing, as well as to review the literature for similar cases.
[h=4]METHODS:[/h] A PubMed search was made using the following search terms: systemic contact dermatitis, formaldehyde, influenza, and vaccine.
[h=4]RESULTS:[/h] A review of the literature revealed 2 cases of systemic contact dermatitis from formaldehyde derived from aspartame and 1 case from a thimerosal-containing influenza vaccine. No cases caused by formaldehyde in influenza or other vaccines were found.
[h=4]CONCLUSION:[/h] This case highlights the importance of considering systemic allergic contact dermatitis in any patient presenting with dermatitis following injection of a formaldehyde-containing vaccine.
? The Author(s) 2015.


[h=4]KEYWORDS:[/h] dermatitis; dermatology

PMID: 25876644 [PubMed - as supplied by publisher]
 
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