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The Quest for a Universal Flu Vaccine: Headless HA 2.0

tetano

Editor, Senior Moderator
Cell Host Microbe. 2015 Oct 14;18(4):395-7. doi: 10.1016/j.chom.2015.10.003.
[h=1]The Quest for a Universal Flu Vaccine: Headless HA 2.0.[/h] Krammer F[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Two recent publications report the design of immunogens based on the conserved stalk domain of the influenza virus hemagglutinin. These new "headless" hemagglutinin constructs recapitulate the epitopes recognized by broadly neutralizing antibodies and induce broadly protective/heterosubtypic immunity in animal models, bringing us a step closer to "universal" influenza virus vaccines.
Copyright ? 2015 Elsevier Inc. All rights reserved.
 
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