Giuseppe
Emeritus
[Source: Thorax, full page: (LINK). Editorial, extract, edited.]
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<CITE><ABBR>Thorax</ABBR> doi:10.1136/thoraxjnl-2012-202885 </CITE>
<CITE></CITE>
<CITE></CITE>PostScript
Correspondence
Amoxycillin-clavulanate for chronic wet cough in children: cautious interpretation of study findings warranted
Patrick Stark 1, Rachel Heenan 1, Francesca Orsani 2, Kim Jachno 2, Tom G Connell 1,3,4
Author Affiliations: <SUP>1</SUP>Department of General Medicine, Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia; <SUP>2</SUP>Clinical Epidemiology and Biostatistics Unit, Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia; <SUP>3</SUP>Department of Paediatrics, University of Melbourne, Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia; <SUP>4</SUP>Murdoch Children's Research Institute, Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia
Correspondence to Dr Tom G Connell, Department of General Medicine, Royal Children's Hospital Melbourne, Flemington Road, Parkville, Melbourne, Victoria 3052, Australia; tom.connell@rch.org.au
Received 18 October 2012 / Revised 18 October 2012 / Accepted 29 November 2012 / Published Online First 22 December 2012
We read with interest the recent paper by Marchant et al comparing amoxicillin-clavunate to placebo for the treatment of chronic wet cough in children.1 The authors should be commended for attempting a randomised controlled clinical trial in this group of patients that often present paediatricians with a management dilemma. Nevertheless, we have significant concerns regarding several aspects of the study methodology, analysis and interpretation and feel that the authors have overstated their conclusions. We therefore urge caution in interpretation of the study findings. First, ?
(?)
-<CITE></CITE>
<CITE></CITE>PostScript
Correspondence
Amoxycillin-clavulanate for chronic wet cough in children: cautious interpretation of study findings warranted
Patrick Stark 1, Rachel Heenan 1, Francesca Orsani 2, Kim Jachno 2, Tom G Connell 1,3,4
Author Affiliations: <SUP>1</SUP>Department of General Medicine, Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia; <SUP>2</SUP>Clinical Epidemiology and Biostatistics Unit, Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia; <SUP>3</SUP>Department of Paediatrics, University of Melbourne, Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia; <SUP>4</SUP>Murdoch Children's Research Institute, Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia
Correspondence to Dr Tom G Connell, Department of General Medicine, Royal Children's Hospital Melbourne, Flemington Road, Parkville, Melbourne, Victoria 3052, Australia; tom.connell@rch.org.au
Received 18 October 2012 / Revised 18 October 2012 / Accepted 29 November 2012 / Published Online First 22 December 2012
We read with interest the recent paper by Marchant et al comparing amoxicillin-clavunate to placebo for the treatment of chronic wet cough in children.1 The authors should be commended for attempting a randomised controlled clinical trial in this group of patients that often present paediatricians with a management dilemma. Nevertheless, we have significant concerns regarding several aspects of the study methodology, analysis and interpretation and feel that the authors have overstated their conclusions. We therefore urge caution in interpretation of the study findings. First, ?
(?)
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