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Transmission dynamics of influenza in two major cities of Uganda

tetano

Editor, Senior Moderator
Epidemics. 2018 Mar 19. pii: S1755-4365(17)30146-9. doi: 10.1016/j.epidem.2018.03.002. [Epub ahead of print]
[h=1]Transmission dynamics of influenza in two major cities of Uganda.[/h] Yang W[SUP]1[/SUP], Cummings MJ[SUP]2[/SUP], Bakamutumaho B[SUP]3[/SUP], Kayiwa J[SUP]3[/SUP], Owor N[SUP]3[/SUP], Namagambo B[SUP]3[/SUP], Byaruhanga T[SUP]3[/SUP], Lutwama JJ[SUP]3[/SUP], O'Donnell MR[SUP]4[/SUP], Shaman J[SUP]5[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] In this paper, we report the epidemic characteristics of the three co-circulating influenza viruses (i.e., A/H1N1, A/H3N2, and B) in two tropical African cities-Kampala and Entebbe, Uganda-over an eight-year period (2008-2015). Using wavelet methods, we show that influenza epidemics recurred annually during the study period. In most months, two or more influenza viruses co-circulated at the same time. However, the epidemic timing differed by influenza (sub)type. Influenza A/H3N2 caused epidemics approximately every 2 years in both cities and tended to alternate with A/H1N1 or B. Influenza A/H1N1 and B produced smaller but more frequent epidemics and biennial epidemics of these two viruses tended to be synchronous. In addition, epidemics of A/H3N2 were more synchronized in the two cities (located ca.37 km apart) than that of A/H1N1 or influenza B.


[h=4]KEYWORDS:[/h] (sub)type specific; Epidemic frequency; Influenza; Tropical regions; Uganda

PMID: 29576517 DOI: 10.1016/j.epidem.2018.03.002
 
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