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UK: Warning on outbreak of deadly diseases due to ageing laboratories

Shiloh

Editor, Senior Moderator
Source: http://www.theherald.co.uk/news/new...eadly_diseases_due_to_ageing_laboratories.php

Poor maintenance and under-investment at British laboratories handling some of the world's most deadly diseases could lead to another devastating leak similar to the one in Surrey which led to last year's foot-and-mouth outbreak.

Parliament's Commons Innovation, Universities, Science and Skills Committee said there was a risk of another "devastating" leak like last year's foot-and-mouth escape from the animal health facility in Pirbright, Surrey, unless biosecurity was taken more seriously.

The committee singled out the "ageing" Health Protection Agency (HPA) laboratories at Porton Down in Wiltshire where it described the conditions as "not acceptable".

It called for the appointment of a single government minister to take responsibility for the co-ordination of biosecurity measures and the provision of "high containment" laboratories.

In all, there are 10 sites in the UK working with the most dangerous pathogens, classified as CL4, with a further 600 operating at the next level down with CL3 pathogens.


The committee said that while some facilities were world-class, others had been neglected and were in need of significant investment.

"The costs to human or animal health and to the economy of a breach of biosecurity at a high-containment laboratory are devastating, as seen at Pirbright in 2007," it said.

"We urge all those who fund high-containment research to consider more seriously the cost of maintaining and running high-containment laboratories. All funders of high-containment laboratories must ensure that long-term funding for running costs is provided, sustained and protected to ensure risk management can take place effectively.


"The government has a particular responsibility in this regard."

It said that decisions were needed urgently on the funding of the redevelopment of the Pirbright site while the Department of Health should consider the redevelopment of the HPA facility at Porton Down as a matter of priority.

"It is not acceptable that scientists at HPA Porton Down are asked to work in such ageing facilities," it said.

The committee said that ministers needed to take a firmer grip on biosecurity with a single minister appointed to take overall responsibility for the issue across government.

"We are disturbed that ministers have not met to discuss the issue of biosecurity, especially given that no organisation or government department has oversight in this area or responsibility for planning for future requirements, for example in the areas of surge capacity and anti-terrorist provision," it said.

The committee also called for improved vetting of staff working at high-containment laboratories.

"Security-vetting is intended to minimise the risks of deliberate misuse of dangerous pathogenic material," it said.


"We therefore recommend the government provide access to government vetting programmes so all those working with CL4 pathogens can be reliably security vetted to a consistent, high standard."

? All rights reserved.
 
Re: UK: Warning on outbreak of deadly diseases due to ageing laboratories

Source: http://www.dailymail.co.uk/news/art...-laboratories-Government-funding-neglect.html

'Deadly diseases could escape from laboratories because of Government funding neglect'

By David Derbyshire
Last updated at 12:30 AM on 25th June 2008

Some of the deadliest and most contagious diseases in the world could escape from British laboratories unless the Government ends decades of neglect, MPs warn today.

They say the security at research centres working with diseases such as anthrax and ebola is being put at risk by poor maintenance and penny-pinching bureaucrats.

Conditions at the Institute for Animal Health at Pirbright in Surrey - where foot and mouth disease escaped last year - and at the ageing Health Protection Agency lab at Porton Down in Wiltshire are singled out as particularly bad.



The Innovation, Universities, Science and Skills Committee warns in a report that there is a risk of another 'devastating' leak unless biosecurity is taken more seriously.

Ten laboratories in Britain work with the most dangerous types of viruses and bacteria.

These 'level four' containment facilities store samples of anthrax, bird flu and bubonic plague and carry out research into the diseases.

Another 600 sites are allowed to work on less dangerous diseases.


MPs describe some facilities as 'world class' - but warn that others had been badly maintained.

'This must be rectified to ensure the incident at Pirbright is not repeated,' the report says.

'A number of high containment laboratories have been neglected and the funding situation is uncertain.

'The Government must ensure that dependable funding is provided to maintain such facilities safely.'

The report calls for a single Government minister to take responsibility for biosecurity.

The official inquiry into last year's foot and mouth outbreak said it was caused by shoddy biosecurity at the Government-funded Institute for Animal Health at Pirbright.

The virus was in waste water leaving the plant but rather than being destroyed it escaped from a cracked drain.

It leaked into a field and was spread to neighbouring farms on the tyres of builders' lorries.


Eight farms were infected, thousands of animals destroyed and farmers lost millions because of livestock restrictions.

The MPs' report says decisions are needed urgently on the future of Pirbright, while the redevelopment of Porton Down should be considered a priority.

'It is not acceptable that scientists at Health Protection Agency Porton Down are asked to work in such ageing facilities,' it says.

The committee also calls for improved vetting of staff working at high containment laboratories.

Although foot and mouth is highly contagious in animals, it does not pose a health risk to humans.

But the accidental release of a disease such as ebola could be devastating. In Africa - where the disease is passed from animals to humans - it kills up to 85 per cent of victims.

Committee chairman Phil Willis said: 'The outbreak of foot and mouth disease at Pirbright highlights that in the long run, proper regulation, running and maintenance of high containment facilities is considerably cheaper than remedying a breach of bio-containment.'
 
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