tetano
Editor, Senior Moderator
Vaccine
. 2021 Oct 30;S0264-410X(21)01387-6.
doi: 10.1016/j.vaccine.2021.10.054. Online ahead of print.
COVID-19 vaccination significantly reduces morbidity and absenteeism among healthcare personnel: A prospective multicenter study
Helena C Maltezou[SUP] 1 [/SUP], Periklis Panagopoulos[SUP] 2 [/SUP], Flora Sourri[SUP] 3 [/SUP], Theodoros V Giannouchos[SUP] 4 [/SUP], Vasilios Raftopoulos[SUP] 5 [/SUP], Maria N Gamaletsou[SUP] 6 [/SUP], Amalia Karapanou[SUP] 7 [/SUP], Dimitra-Maria Koukou[SUP] 8 [/SUP], Athanasia Koutsidou[SUP] 9 [/SUP], Emmanuela Peskelidou[SUP] 10 [/SUP], Konstantina Papanastasiou[SUP] 11 [/SUP], Kyriakos Souliotis[SUP] 12 [/SUP], Athanasia Lourida[SUP] 13 [/SUP], Nikolaos V Sipsas[SUP] 6 [/SUP], Dimitrios Hatzigeorgiou[SUP] 14 [/SUP]
Affiliations
Abstract
Aim: Healthcare personnel (HCP) are prioritized for coronavirus disease 2019 (COVID-19) vaccination to protect them and non-disruptive provision of healthcare services. We assessed the impact of the Pfizer-BioNTech vaccine on morbidity and absenteeism among HCP.
Methods: We studied 7445 HCP in five tertiary-care hospitals in Greece from November 15, 2020 through April 18, 2021.
Results: A total of 910 episodes of absenteeism and 9695 days of absence were recorded during the entire study period. Starting from January 4, 2021, 4823/7445 HCP (64.8%) were fully or partially vaccinated. Overall, 535 episodes of absenteeism occurred from January 4, 2021 through April 18, 2021, including 309 (57.76%) episodes among 2622 unvaccinated HCP and 226 (42.24%) episodes among 4823 vaccinated HCP (11.8 versus 4.7 episodes of absenteeism per 100 HCP, respectively; p-value < 0.001). The mean duration of absenteeism was 11.9 days among unvaccinated HCP compared with 6.9 days among vaccinated HCP (p-value < 0.001). Unvaccinated HCP more frequently developed acute respiratory infection, influenza-like illness, and COVID-19 (p-values < 0.001 for all comparisons). Vaccine effectiveness for fully vaccinated HCP was estimated at 94.16% [confidence interval (CI): 88.50%-98.05%) against COVID-19, 83.62% (CI: 73.36%-90.38%) against SARS-CoV-2 infection (asymptomatic or COVID-19), and 66.42% (CI: 56.86%-74.15%) against absenteeism.
Conclusion: The COVID-19 pandemic had a considerable impact on healthcare workforce. The Pfizer-BioNTech vaccine significantly reduced morbidity, COVID-19, absenteeism and duration of absenteeism among HCP during a period of high SARS-CoV-2 circulation in the community. It is expected that HCP vaccination will protect them and healthcare services and contain healthcare costs.
Keywords: Absenteeism; COVID-19; Healthcare personnel; Morbidity; Vaccination.
. 2021 Oct 30;S0264-410X(21)01387-6.
doi: 10.1016/j.vaccine.2021.10.054. Online ahead of print.
COVID-19 vaccination significantly reduces morbidity and absenteeism among healthcare personnel: A prospective multicenter study
Helena C Maltezou[SUP] 1 [/SUP], Periklis Panagopoulos[SUP] 2 [/SUP], Flora Sourri[SUP] 3 [/SUP], Theodoros V Giannouchos[SUP] 4 [/SUP], Vasilios Raftopoulos[SUP] 5 [/SUP], Maria N Gamaletsou[SUP] 6 [/SUP], Amalia Karapanou[SUP] 7 [/SUP], Dimitra-Maria Koukou[SUP] 8 [/SUP], Athanasia Koutsidou[SUP] 9 [/SUP], Emmanuela Peskelidou[SUP] 10 [/SUP], Konstantina Papanastasiou[SUP] 11 [/SUP], Kyriakos Souliotis[SUP] 12 [/SUP], Athanasia Lourida[SUP] 13 [/SUP], Nikolaos V Sipsas[SUP] 6 [/SUP], Dimitrios Hatzigeorgiou[SUP] 14 [/SUP]
Affiliations
- PMID: 34740473
- DOI: 10.1016/j.vaccine.2021.10.054
Abstract
Aim: Healthcare personnel (HCP) are prioritized for coronavirus disease 2019 (COVID-19) vaccination to protect them and non-disruptive provision of healthcare services. We assessed the impact of the Pfizer-BioNTech vaccine on morbidity and absenteeism among HCP.
Methods: We studied 7445 HCP in five tertiary-care hospitals in Greece from November 15, 2020 through April 18, 2021.
Results: A total of 910 episodes of absenteeism and 9695 days of absence were recorded during the entire study period. Starting from January 4, 2021, 4823/7445 HCP (64.8%) were fully or partially vaccinated. Overall, 535 episodes of absenteeism occurred from January 4, 2021 through April 18, 2021, including 309 (57.76%) episodes among 2622 unvaccinated HCP and 226 (42.24%) episodes among 4823 vaccinated HCP (11.8 versus 4.7 episodes of absenteeism per 100 HCP, respectively; p-value < 0.001). The mean duration of absenteeism was 11.9 days among unvaccinated HCP compared with 6.9 days among vaccinated HCP (p-value < 0.001). Unvaccinated HCP more frequently developed acute respiratory infection, influenza-like illness, and COVID-19 (p-values < 0.001 for all comparisons). Vaccine effectiveness for fully vaccinated HCP was estimated at 94.16% [confidence interval (CI): 88.50%-98.05%) against COVID-19, 83.62% (CI: 73.36%-90.38%) against SARS-CoV-2 infection (asymptomatic or COVID-19), and 66.42% (CI: 56.86%-74.15%) against absenteeism.
Conclusion: The COVID-19 pandemic had a considerable impact on healthcare workforce. The Pfizer-BioNTech vaccine significantly reduced morbidity, COVID-19, absenteeism and duration of absenteeism among HCP during a period of high SARS-CoV-2 circulation in the community. It is expected that HCP vaccination will protect them and healthcare services and contain healthcare costs.
Keywords: Absenteeism; COVID-19; Healthcare personnel; Morbidity; Vaccination.