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Source:
http://www.publico.es/361882/vacuna-no-reduce-la-cantidad-de-neumonias-infantiles-en-eeuu
Spanish to English translation
Vaccine does not reduce the amount of U.S. child pneumonia
Reuters 17/02/2011 15:57 Updated: 02/17/2011 17:05
By Frederik Joelving
Pediatric vaccine against pneumococcal bacteria used in the United States since 2000 did not leave a visible mark on the disease.
In the first study to provide national figures for childhood pneumonia, the authors found that rates of lung infection remained more or less stable between 1994 and 2007.
At the beginning of this period were diagnosed with pneumonia and 19 of every 1,000 children, compared with 22 out of 1,000 at the end. But that does not mean the vaccine Prevnar or PCV7 (from Pfizer) was useless. A previous study, for example, found that the number of children treated for pneumonia in a hospital had decreased by more than half with the introduction of the vaccine.
"It is possible that vaccination has had an impact on the most serious complications of pneumonia," said Dr. Samir S. Shah, School of Medicine, University of Pennsylvania in Philadelphia, who led the study.
Prevnar protects against the bacterium Streptococcus pneumoniae, or pneumococcus, which causes a variety of infections, including pneumonia, meningitis and middle ear infection.
"If you analyze the effectiveness of the vaccine in reducing cases of meningitis and blood infections, the result is phenomenal," said Shah, whose study was supported by the National Institutes of Health U.S..
While Pfizer reported that Prevnar is approved in the United States against pneumonia, said the new study design could mask possible effects of vaccination on the disease.
Since many other microbes, including viruses, can cause pneumonia, analyze all cases overshadow any potential effects it may have Prevnar.
"This study lacks data on the cause of pneumonia recorded in these databases. One problem in interpreting studies like this (...) is that the results may include a decrease in real value," said Kim Center, Pfizer.
Each year, more than a million Americans end up hospitalized with pneumonia. In 2007 alone 52,000 people died from the disease, according to the Centers for Disease Control and Prevention (CDC).
In children under 5 years, the pneumococcus causes 5,000 annual cases of meningitis, blood infections and other serious ailments.
The new study, published in the journal Pediatrics, also found that most doctors use broad-spectrum antibiotics to treat pneumonia, although there are more effective specific drugs such as penicillin.
"The problem is, if prescribed a lot of these antibiotics, increased resistance to treatment in the community," said Shah.
SOURCE: Pediatrics, online February 14, 2011
http://www.publico.es/361882/vacuna-no-reduce-la-cantidad-de-neumonias-infantiles-en-eeuu
Spanish to English translation
Vaccine does not reduce the amount of U.S. child pneumonia
Reuters 17/02/2011 15:57 Updated: 02/17/2011 17:05
By Frederik Joelving
Pediatric vaccine against pneumococcal bacteria used in the United States since 2000 did not leave a visible mark on the disease.
In the first study to provide national figures for childhood pneumonia, the authors found that rates of lung infection remained more or less stable between 1994 and 2007.
At the beginning of this period were diagnosed with pneumonia and 19 of every 1,000 children, compared with 22 out of 1,000 at the end. But that does not mean the vaccine Prevnar or PCV7 (from Pfizer) was useless. A previous study, for example, found that the number of children treated for pneumonia in a hospital had decreased by more than half with the introduction of the vaccine.
"It is possible that vaccination has had an impact on the most serious complications of pneumonia," said Dr. Samir S. Shah, School of Medicine, University of Pennsylvania in Philadelphia, who led the study.
Prevnar protects against the bacterium Streptococcus pneumoniae, or pneumococcus, which causes a variety of infections, including pneumonia, meningitis and middle ear infection.
"If you analyze the effectiveness of the vaccine in reducing cases of meningitis and blood infections, the result is phenomenal," said Shah, whose study was supported by the National Institutes of Health U.S..
While Pfizer reported that Prevnar is approved in the United States against pneumonia, said the new study design could mask possible effects of vaccination on the disease.
Since many other microbes, including viruses, can cause pneumonia, analyze all cases overshadow any potential effects it may have Prevnar.
"This study lacks data on the cause of pneumonia recorded in these databases. One problem in interpreting studies like this (...) is that the results may include a decrease in real value," said Kim Center, Pfizer.
Each year, more than a million Americans end up hospitalized with pneumonia. In 2007 alone 52,000 people died from the disease, according to the Centers for Disease Control and Prevention (CDC).
In children under 5 years, the pneumococcus causes 5,000 annual cases of meningitis, blood infections and other serious ailments.
The new study, published in the journal Pediatrics, also found that most doctors use broad-spectrum antibiotics to treat pneumonia, although there are more effective specific drugs such as penicillin.
"The problem is, if prescribed a lot of these antibiotics, increased resistance to treatment in the community," said Shah.
SOURCE: Pediatrics, online February 14, 2011