tetano
Editor, Senior Moderator
Virol J
. 2022 Feb 10;19(1):29.
doi: 10.1186/s12985-022-01754-w.
A UV-LED module that is highly effective at inactivating human coronaviruses and HIV-1
Arvin T Persaud[SUP] #[/SUP][SUP] 1 2 [/SUP], Jonathan Burnie[SUP] #[/SUP][SUP] 1 2 [/SUP], Laxshaginee Thaya[SUP] 1 2 [/SUP], Liann DSouza[SUP] 3 [/SUP], Steven Martin[SUP] 3 [/SUP], Christina Guzzo[SUP] 4 5 [/SUP]
Affiliations
Abstract
Ultraviolet (UV) light has previously been established as useful method of disinfection, with demonstrated efficacy to inactivate a broad range of microorganisms. The advent of ultraviolet light-emitting diodes provides advantages in ease of disinfection, in that there can be delivery of germicidal UV with the same light unit that delivers standard white light to illuminate a room. Herein we demonstrate the efficacy and feasibility of ultraviolet light-emitting diodes as a means of decontamination by inactivating two distinct virus models, human coronavirus 229E and human immunodeficiency virus. Importantly, the same dose of ultraviolet light that inactivated human viruses also elicited complete inactivation of ultraviolet-resistant bacterial spores (Bacillus pumilus), a gold standard for demonstrating ultraviolet-mediated disinfection. This work demonstrates that seconds of ultraviolet light-emitting diodes (UV-LED) exposure can inactivate viruses and bacteria, highlighting that UV-LED could be a useful and practical tool for broad sanitization of public spaces.
Keywords: Bacillus pumilus; Human coronavirus (hCoV); Human immunodeficiency virus (HIV); Light emitting diode (LED); UV disinfection; UV sanitization; Ultraviolet light (UV); Virus inactivation.
. 2022 Feb 10;19(1):29.
doi: 10.1186/s12985-022-01754-w.
A UV-LED module that is highly effective at inactivating human coronaviruses and HIV-1
Arvin T Persaud[SUP] #[/SUP][SUP] 1 2 [/SUP], Jonathan Burnie[SUP] #[/SUP][SUP] 1 2 [/SUP], Laxshaginee Thaya[SUP] 1 2 [/SUP], Liann DSouza[SUP] 3 [/SUP], Steven Martin[SUP] 3 [/SUP], Christina Guzzo[SUP] 4 5 [/SUP]
Affiliations
- PMID: 35144624
- DOI: 10.1186/s12985-022-01754-w
Abstract
Ultraviolet (UV) light has previously been established as useful method of disinfection, with demonstrated efficacy to inactivate a broad range of microorganisms. The advent of ultraviolet light-emitting diodes provides advantages in ease of disinfection, in that there can be delivery of germicidal UV with the same light unit that delivers standard white light to illuminate a room. Herein we demonstrate the efficacy and feasibility of ultraviolet light-emitting diodes as a means of decontamination by inactivating two distinct virus models, human coronavirus 229E and human immunodeficiency virus. Importantly, the same dose of ultraviolet light that inactivated human viruses also elicited complete inactivation of ultraviolet-resistant bacterial spores (Bacillus pumilus), a gold standard for demonstrating ultraviolet-mediated disinfection. This work demonstrates that seconds of ultraviolet light-emitting diodes (UV-LED) exposure can inactivate viruses and bacteria, highlighting that UV-LED could be a useful and practical tool for broad sanitization of public spaces.
Keywords: Bacillus pumilus; Human coronavirus (hCoV); Human immunodeficiency virus (HIV); Light emitting diode (LED); UV disinfection; UV sanitization; Ultraviolet light (UV); Virus inactivation.