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Virol J . SARS-CoV-2: characteristics and current advances in research

tetano

Editor, Senior Moderator
Virol J


. 2020 Jul 29;17(1):117.
doi: 10.1186/s12985-020-01369-z.
SARS-CoV-2: characteristics and current advances in research


Yicheng Yang[SUP] 1 2 [/SUP], Zhiqiang Xiao[SUP] 3 [/SUP], Kaiyan Ye[SUP] 4 [/SUP], Xiaoen He[SUP] 2 [/SUP], Bo Sun[SUP] 1 [/SUP], Zhiran Qin[SUP] 2 [/SUP], Jianghai Yu[SUP] 2 [/SUP], Jinxiu Yao[SUP] 5 [/SUP], Qinghua Wu[SUP] 2 [/SUP], Zhang Bao[SUP] 6 [/SUP], Wei Zhao[SUP] 7 [/SUP]



Affiliations

Abstract

Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has spread rapidly across the world and become an international public health emergency. Both SARS-CoV-2 and SARS-CoV belong to subfamily Coronavirinae in the family Coronaviridae of the order Nidovirales and they are classified as the SARS-like species while belong to different cluster. Besides, viral structure, epidemiology characteristics and pathological characteristics are also different. We present a comprehensive survey of the latest coronavirus-SARS-CoV-2-from investigating its origin and evolution alongside SARS-CoV. Meanwhile, pathogenesis, cardiovascular disease in COVID-19 patients, myocardial injury and venous thromboembolism induced by SARS-CoV-2 as well as the treatment methods are summarized in this review.

Keywords: COVID-19; Cardiovascular disease; Cytokine storm; Myocardial injury; SARS-CoV-2; Treatment; Venous thromboembolism.
 
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