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Vt. baby diagnosed with rare type of meningitis

Shiloh

Editor, Senior Moderator
Source: http://www.wcax.com/story/28024400/v...-of-meningitis
Vt. baby diagnosed with rare type of meningitis

Posted: Feb 04, 2015 1:50 PM EST Updated: Feb 04, 2015 7:13 PM EST By Bridget Barry Caswell
BURLINGTON, Vt. - Inside a room at the University of Vermont Children's Hospital, 7-month-old Zakeyah Ferguson sleeps peacefully. She's been here for three weeks now-- the first two on a ventilator-- in a medically induced coma in the intensive care unit. She's battling bacterial meningitis.
"They knew something was wrong. Her fever went from 102 to 105.2 in two hours, and that was with Tylenol and ibuprofen in her," mom Kassie Ferguson said.
Zakeyah's mother and father say she declined rapidly in a matter of hours last month before doctors near their North Troy home in the Northeast Kingdom did a spinal tap, confirmed her life-threatening diagnosis and sent her to Burlington...
 
She has serotype 15B, the group that apparently emerged as a replacement virus exploiting the ecological niche vacated by use of PCV13 vaccine. It is invasive through the mucous membranes of the nose and antibiotic resistant.

Increase in the nasopharyngeal carriage of non-vaccine serogroup 15 Streptococcus pneumoniae after introduction of children pneumococcal conjugate vaccination in Hong Kong Diagnostic Microbiology and Infectious Disease
Volume 81, Issue 2, February 2015, Pages 145?148

Highlights


?We assessed pneumococcal carriage in children <5 years in Hong Kong, 2010?2013. ?We investigated serotype replacement in relation to pneumococcal vaccine use. ?An increase in carriage of serogroup 15 isolates was observed. ?Carriage of serogroup 15 was associated with pneumococcal vaccine use. ?Increasing serogroup 15 was a result of expansion of clones. ...
The finding highlights the emergence of serogroup 15 following PCV13 use.
http://www.sciencedirect.com/science...32889314004568
 
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