Worldwide: 24 confirmed cases due to novel animal nCoV coronavirus - 16 fatalities - September 20, 2012 - May 2, 2013

[alert]

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 13 confirmed cases due to novel animal coronavirus - 7 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 13 confirmed cases due to novel animal coronavirus - 7 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Here's some more details about cases #10 and #11:

http://www.healthaim.com/deadly-virus-could-cause-problems-worldwide/

Deadly Virus Could Cause Problems Worldwide
Posted by David Arnold on Mar 2nd, 2013 // No Comments

Khalid Hussain was the first person from Britain who died from the new SARS-type virus in late February. Hussain was just 38 and died at a hospital in Birmingham, England after his father infected him. His father had just returned from a trip to Mecca, when Hussain become sick.

The symptoms of the SARS-like coronavirus are shortness of breath, a strong cough and a fever. Those symptoms are similar to a common cold. Shortly afterwards, breathing becomes difficult and the lips on the person start to turn blue.

[snip]

 

[alert]

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 13 confirmed cases due to novel animal coronavirus - 7 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 13 confirmed cases due to novel animal coronavirus - 7 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Saudi Arabia has confirmed an additional fatal case, the 14th case worldwide and the 8th fatality:

http://www.flutrackers.com/forum/showthread.php?t=201542

 

[alert]

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 14 confirmed cases due to novel animal coronavirus - 8 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 14 confirmed cases due to novel animal coronavirus - 8 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Let us not also forget that 2 of the 6 non-fatal cases (#2 and #10) are still ill, so if one were to calculate the CFR based only on cases that have reached a final outcome, the apparently CFR would be 66.7%, 8 deaths in 12 cases.

Published Date: 2013-03-06 19:06:11
Subject: PRO/AH/EDR> Novel coronavirus - Eastern Mediterranean (07): Saudi Arabia, WHO
Archive Number: 20130306.1574423

NOVEL CORONAVIRUS - EASTERN MEDITERRANEAN (07): SAUDI ARABIA, WHO
*****************************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org

Date: 6 Mar 2013
Source: WHO GAR (Global Alert and Response) [edited]
http://www.who.int/csr/don/2013_03_06/en/index.html


Novel coronavirus infection - update 6 Mar 2013
-------------------
The Ministry of Health in Saudi Arabia has informed WHO of a new confirmed case of infection with the novel coronavirus (NCoV).

The patient, a 69-year-old male, was hospitalized on [10 Feb 2013] and died on [19 Feb 2013]. Preliminary investigation indicated that the patient had no contact with previously reported cases of NCoV infection and did not have recent history of travel.

To date, WHO has been informed of a global total of 14 confirmed cases of human infection with NCoV, including 8 deaths. Of the total number, 7 cases, including 5 deaths, have been reported from Saudi Arabia.

Based on the current situation and available information, WHO encourages all Member States (MS) to continue their surveillance for severe acute respiratory infections (SARI) and to carefully review any unusual patterns. WHO is currently working with international experts and countries where cases have been reported to assess the situation and review recommendations for surveillance and monitoring.

All MS are reminded to promptly assess and notify WHO of any new case of infection with NCoV along with information about potential exposures that may have resulted in infection and a description of the clinical course.

WHO does not advise special screening at points of entry with regard to this event nor does it recommend that any travel or trade restrictions be applied.

WHO continues to closely monitor the situation.

--
Communicated by:
ProMED-mail Rapporteur Marianne Hopp

[As stated above, the current total number of confirmed cases of illness associated with infection with the novel coronavirus (nCoV) is now 14, of which 8 had a fatal outcome, a case fatality rate (CFR) of 57 percent. As the total number of confirmed cases to date is small (14), the observed CFR of 57 may be a reflection of non-confirmation of milder illness associated with infection with this nCoV.

The breakdown of cases (and deaths) by country of report is:
- Saudi Arabia: 7 (5 deaths)
- Jordan: 2 (2 deaths)
- UK: 4 (1 patient from Qatar - under treatment, 3 patients from UK - one with history of travel to Saudi Arabia and Pakistan prior to illness; 1 under treatment, 1 recovered, 1 death)
- Germany: 1 (patient from Qatar - discharged).

More information on the epidemiologic investigation surrounding this case's potential exposures, such as animals, including bats, would be greatly appreciated.

 

[alert]

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 14 confirmed cases due to novel animal coronavirus - 8 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 14 confirmed cases due to novel animal coronavirus - 8 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Saudi Arabia has confirmed an additional fatal case:

http://www.flutrackers.com/forum/showthread.php?t=201891

bringing the worldwide total to 15 cases, 9 deaths.

 

[alert]

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 14 confirmed cases due to novel animal coronavirus - 8 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 14 confirmed cases due to novel animal coronavirus - 8 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Saudi Arabia has confirmed an additional fatal case:

http://www.flutrackers.com/forum/showthread.php?t=201891

bringing the worldwide total to 15 cases, 9 deaths.

And a contact of that case who had a mild illness has been confirmed to be case #16:

http://www.flutrackers.com/forum/showthread.php?t=202423

 

[alert]

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 16 confirmed cases due to novel animal coronavirus - 9 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 16 confirmed cases due to novel animal coronavirus - 9 fatalities, at least 2 cases still in hospital - September 20, 2012 +

Hat-tip Treyfish. Case #10 has died:

http://www.birminghammail.co.uk/lifestyle/health/birmingham-grandad-abid-hussain-uks-1877516

Birmingham grandad is UK's second Coronavirus victim
23 Mar 2013 09:00
Abid Hussain, of Winson Green, lost battle against Sars-like bug in hospital on Tuesday

Birmingham grandad Abid Hussain has become the UK’s second victim to the new Sars-like bug Coronavirus.

The tragedy comes as Mr Hussain’s wife and daughter were in Pakistan after burying his son Khalid, 38, who had also fallen victim to the killer disease.

The dad-of-two, in his 60s, of Winson Green, was being treated at Wythenshawe Hospital, in Manchester, and seemed to be improving.

But he took a turn for the worse and lost his battle on Tuesday.

[snip]

------------

[Now 2/3 of the confirmed cases that have reached a final outcome (10 of 15) have died, with case #2 possibly still hospitalized since September 2012. - alert]

 

[Treyfish]

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 16 confirmed cases due to novel animal coronavirus - 10 fatalities, 1 case still in hospital - September 20, 2012 +

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 16 confirmed cases due to novel animal coronavirus - 10 fatalities, 1 case still in hospital - September 20, 2012 +

Patient released after coronavirus treatment


Last Update 24 March 2013 2:29 am
There was another case of coronavirus infection in the Kingdom, according to the World Health Organization (WHO).
Ziad Al-Memish, undersecretary to the Ministry of Health for Public Health, confirmed the new case. ?It was a mild infection in a person from Riyadh and the patient is already discharged from the hospital after complete recovery,? Al-Memish said.
The undersecretary said that there was no cause for alarm about the infection as the ministry had already taken all preventive measures to keep the disease under control.
The official also pointed out that people need not worry about the virus as it is believed that it cannot be transmitted from person to person. Still, he cautioned people to take measures to avoid the virus.
?We are also monitoring the virus in all parts of the Kingdom through the regional directorates of the MoH,? he said.
Al-Memish, who is also the chairman of the National Scientific Committee for Infectious Diseases, said that only a few people had been found positive in the world.
Symptoms of the virus include runny nose, general feeling of illness, mild sore throat, cough, headache, low fever and chills. It can also cause respiratory, intestinal and neurological illness.
The official said most of those infected recover completely with no complications after receiving the required supportive therapy.
To date four countries have recorded infections: Saudi Arabia with nine cases and six deaths; Qatar with two cases; Britain with three cases and one death; and Jordan with two fatal cases. :tiphat:http://arabnews.com/news/445886?

 

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Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 16 confirmed cases due to novel animal coronavirus - 10 fatalities, 1 case still in hospital - September 20, 2012 +

Re: Saudi Arabia, Qatar, Jordan, United Kingdom: 16 confirmed cases due to novel animal coronavirus - 10 fatalities, 1 case still in hospital - September 20, 2012 +

Germany has imported a case from the UAE, who has since died:

http://www.flutrackers.com/forum/showthread.php?t=202496

becoming the 17th case and 11th fatality.

In addition to updating the counts in this thread, I am changing the location listed to "Worldwide" (as ProMED did for SARS on March 15, 2003) rather than trying to expand the list of countries or to differentiate between countries that experienced local transmission and those that only reported imported cases. Besides, WHO guildlines currently do suggest that clusters of unexplained SARI should be tested for NCoV, no matter where in the world they occur.

 

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Re: Worldwide: 17 confirmed cases due to novel animal coronavirus - 11 fatalities, 1 case still in hospital - September 20, 2012 +

Re: Worldwide: 17 confirmed cases due to novel animal coronavirus - 11 fatalities, 1 case still in hospital - September 20, 2012 +

From the comments on:

http://www.promedmail.org/direct.php?id=20130326.1604564

[snip]

[The above mentioned cases were reported in earlier ProMED-mail posts, including a media report announcing the death of the case in the UK (see Novel coronavirus - Eastern Mediterranean (13): Germany ex UAE 20130326.1603038 and Novel coronavirus - Eastern Mediterranean (12): KSA, UK fatality, RFI 20130323.1600113).

As of today, 26 Mar 2013, the breakdown of cases (and deaths) by country of report is:
- Saudi Arabia: 9 (6 deaths)
- Jordan: 2 (2 deaths)
- UK: 4 (one patient from Qatar -- under treatment, 3 patients from UK -- one with history of travel to Saudi Arabia and Pakistan prior to illness; one recovered, 2 deaths)
- Germany: 2 (one patient from Qatar -- discharged, one patient from the UAE - one death).

As mentioned in the above WHO release, the total number of confirmed nCoV cases is now 17 with 11 deaths, bringing the case fatality ratio to 64.7 percent. Caution in interpretation of this figure as the numbers of cases is still very low and the ability to detect prior mild infections with this specific coronavirus is presently absent. Given the histories of other respiratory illnesses in contacts of cases that were relatively mild and associated with full recovery, but tested negative for infection with the nCoV, the possibility that there are more infections associated with milder disease is there.

In the report of the Jordanian cluster, there were a total of 11 individuals reported to have had respiratory illnesses, with confirmation of nCoV infection in specimens from the 2 fatal cases only (see prior ProMED-mail reports: Novel coronavirus - Eastern Mediterranean: WHO, Jordan, conf., RFI 20121130.1432498 and Novel coronavirus - Saudi Arabia (04): RFI, Jordan, April 2012 20120925.1308001).

More information on the epidemiologic investigations of this newest case would be greatly appreciated.

 

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Re: Worldwide: 17 confirmed cases due to novel animal coronavirus - 11 fatalities, 1 case still in hospital - September 20, 2012 +

Re: Worldwide: 17 confirmed cases due to novel animal coronavirus - 11 fatalities, 1 case still in hospital - September 20, 2012 +

We only have 11 deaths in our count. Might this mean the hospitalized case from September 2012 has died?

http://www.who.int/csr/disease/coronavirus_infections/update_20130424/en/index.html

Novel coronavirus summary and literature update ? as of 24 April 2013
As of 24 April 2013, 17 cases of human infection with novel coronavirus (nCoV) have been reported to WHO: two from Jordan, two from Qatar, 10 cases from Saudi Arabia, two from the United Kingdom (UK), and one from the United Arab Emirates. Most patients are male (81.3%; 13 of 16 cases with gender reported) and range in age from 25 to 73 years old (median 45 years old). The first cases had onset of illness in late March or early April 2012, the most recent case reported had onset on 8 March 2013. Most patients presented with severe acute respiratory disease requiring hospitalization, and at least 11 have required mechanical ventilation or other advanced respiratory support. Only 2 of the 17 presented with mild disease. Twelve patients have died. One was co-infected with influenza A virus.

Four clusters of cases have been identified. The first occurred in April 2012 in a health care setting in Jordan, with 2 confirmed cases, and 11 probable cases. Both of the confirmed cases died. Ten of the 13 persons in this cluster were health care workers. Two additional clusters occurred among family contacts of cases in Saudi Arabia and one among family members of a resident of the United Kingdom who had recently visited Saudi Arabia. Human-to-human transmission can be confirmed only in the latter as none of the family members who were infected had recently been outside of the United Kingdom and their only known exposure was to the first case (see UKHPA reference below). No sustained community transmission was observed in any of the clusters.

Although some of the cases may have become infected from animal exposures and zoonotic transmission, information on animal exposures is limited. An animal reservoir has not been identified. Investigations into animal sources are on-going.

Four viruses from the United Kingdom (n=2), Saudi Arabia (n=1) and Jordan (n=1) have been cultured and complete genome sequences have been posted to GenBank, a public database. All four of the viruses have a high degree of genetic similarity. Analyses show that the viruses are similar to a bat virus. It should be noted, however, that the similarity of the human virus to the bat virus does not necessarily imply that bats are the reservoir for the human virus. Given the living environment of most of the patients, direct exposure to bats appears unlikely.

 

[Shiloh]

Re: Worldwide: 24 confirmed cases due to novel animal coronavirus - 16 fatalities, 1 case still in hospital - September 20, 2012 +

Re: Worldwide: 24 confirmed cases due to novel animal coronavirus - 16 fatalities, 1 case still in hospital - September 20, 2012 +

Source: http://www.vancouversun.com/Health/...fatal+Saudi+Arabia+reveals/8327194/story.html


7 new coronavirus cases, five fatal, Saudi Arabia reveals; case count reaches 24

By Helen Branswell, The Canadian Press May 2, 2013 8:48 AM

...Saudi Arabia revealed today that it has recorded seven new cases of the mysterious infection recently, and five of the people are already dead.

That brings the total case count for the new disease to 24 cases, with 16 deaths.

There were few details in the official Saudi announcement and no indication of whether the cases might have been linked...