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2009 H1N1: risk factors for hospitalization in a matched case-control study

tetano

Editor, Senior Moderator
Eur J Pediatr. 2012 Mar 21. [Epub ahead of print]
2009 H1N1: risk factors for hospitalization in a matched case-control study.
Launes C, Garc?a-Garc?a JJ, Mart?nez-Planas A, Moraga F, Astigarraga I, Ar?stegui J, Korta J, Salado C, Quintana JM, Soldevila N, Dom?nguez A; the CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain.
Source

Paediatrics Department, Hospital Sant Joan de D?u, University of Barcelona, P. St. Joan de Deu, 2, 08950 Esplugues de Llobregat, Barcelona, Spain.
Abstract

In order to compare sociodemographical data and preexisting risk medical conditions in patients requiring hospital admission for 2009 pandemic influenza A (H1N1) virus infection and those managed on an outpatient basis, a prospective observational, matched case-control study in 36 hospitals of the Spanish National Health Service was conducted from July 2009 to February 2010. Cases were patients aged 6 months to 18 years hospitalized for influenza syndrome, in whom 2009 influenza A (H1N1) virus infection was confirmed using real-time reverse-transcription polymerase chain reaction. Controls were patients aged 6 months to 18 years with confirmed 2009 influenza A (H1N1) infection managed on an outpatient basis. There were 195 cases and 184 controls. In a multivariate model, hospitalization was more frequent in children aged <2 years (odds ratio (OR), 13.8; 95% confidence interval (CI), 1.7-106.4), those with neurological and/or neuromuscular diseases (OR, 3.0; 95% CI, 1.1-8.2), and those whose parents had less than a secondary educational level (OR, 2.7; 95% CI, 1.4-5.2). Children aged <2 years, children with neurological diseases, and children from families with a lower educational status had a higher risk of hospitalization due to influenza A (H1N1) 2009 infection.

PMID:
22430351
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/22430351
 
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