tetano
Editor, Senior Moderator
Clin Vaccine Immunol. 2012 Jan 11. [Epub ahead of print]
A comparison of immunoglobulin G (IgG) subclass concentrations in severe community-acquired pneumonia and severe Pandemic 2009 Influenza A (H1N1) infection.
Gordon CL, Holmes NE, Grayson ML, Torresi J, Johnson PD, Cheng AC, Charles PG.
Source
Department of Infectious Diseases, Austin Health.
Abstract
We compared immunoglobulin G (IgG) subclasses in patients with severe non-influenza community-acquired pneumonia (CAP) to those with severe Pandemic 2009 influenza (H1N1) infection. Low IgG(1) and IgG(2) occurred often in the CAP group; however, H1N1 patients had lower IgG(1) and IgG(2) (5.4 vs. 3.3g/L, p=0.008; 2.5 vs. 1.2g/L, p<0.001, respectively). Low IgG(2) may be specifically linked to severe H1N1, however, it is not clear whether this association is related to H1N1 or to other features of severity.
PMID:
22237894
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22237894
A comparison of immunoglobulin G (IgG) subclass concentrations in severe community-acquired pneumonia and severe Pandemic 2009 Influenza A (H1N1) infection.
Gordon CL, Holmes NE, Grayson ML, Torresi J, Johnson PD, Cheng AC, Charles PG.
Source
Department of Infectious Diseases, Austin Health.
Abstract
We compared immunoglobulin G (IgG) subclasses in patients with severe non-influenza community-acquired pneumonia (CAP) to those with severe Pandemic 2009 influenza (H1N1) infection. Low IgG(1) and IgG(2) occurred often in the CAP group; however, H1N1 patients had lower IgG(1) and IgG(2) (5.4 vs. 3.3g/L, p=0.008; 2.5 vs. 1.2g/L, p<0.001, respectively). Low IgG(2) may be specifically linked to severe H1N1, however, it is not clear whether this association is related to H1N1 or to other features of severity.
PMID:
22237894
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22237894