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Absence of Influenza A(H1N1) During Seasonal and Pandemic Seasons in a Sentinel Nursing Home Surveillance Network in the Netherlands

tetano

Editor, Senior Moderator
Journal of the American Geriatrics Society

Absence of Influenza A(H1N1) During Seasonal and Pandemic Seasons in a Sentinel Nursing Home Surveillance Network in the Netherlands

Remko Enserink MSc1,*,
Adam Meijer PhD2,
Frederika Dijkstra MSc1,
Birgit van Benthem PhD1,
Jenny T. van der Steen PhD3,
Anja Haenen MSc1,
Hans van Delden PhD4,
Herman Cools MD, PhD5,
Marianne van der Sande PhD, MD1,4,
Marie-Jose Veldman-Ariesen PhD1,
on behalf of the Sentinel Surveillance Network on Infectious Diseases in Nursing Homes Study Group?

Article first published online: 31 OCT 2011

DOI: 10.1111/j.1532-5415.2011.03715.x

Objectives

To describe the epidemiological, virological, and institutional characteristics of influenza-like illness (ILI) in nursing homes (NHs).
Design

Continuous clinical surveillance of ILI and virological surveillance of ILI and other acute respiratory infections (ARIs) during four influenza seasons.
Setting

National sentinel NH surveillance network.
Participants

National sentinel residents.
Measurements

Weekly registration of ILI cases (influenza seasons 2008/09?2009/10), influenza virus detection (influenza seasons 2006/07?2009/10), and collection of institutional characteristics of NHs at start of participation.
Results

During the 2008/09 influenza season, ILI incidence started to rise in Week 49 of 2008, peaked in Week 3 of 2009 (158 cases per 10,000 resident weeks), and flattened out by Week 16 of 2009 (mean ILI incidence during epidemic: 73 cases per 10,000 resident weeks). During the 2009/10 influenza pandemic, there was no epidemic peak. Influenza virus type and subtype varied throughout virological surveillance but was limited to influenza A(H3N2) and B viruses. Higher staff vaccination coverage (>15%) was associated with lower ILI-incidence in the 2008/09 influenza season in a univariate negative binomial regression analysis (incidence rate ratio = 0.3, 95% confidence interval = 0.1?0.8)).
Conclusion

Neither seasonal nor pandemic influenza A(H1N1) viruses were detected in the network, despite widespread community transmission of seasonal and influenza A(H1N1) virus. ILI incidence trends corresponded to virological trends. Sentinel surveillance of ILI combining clinical and virological data in NHs increases understanding of transmission risks in this specific vulnerable population.

http://onlinelibrary.wiley.com/doi/...+5+Nov+from+10-12+GMT+for+monthly+maintenance
 
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