tetano
Editor, Senior Moderator
Acta Otolaryngol
. 2023 Jun 16;1-6.
doi: 10.1080/00016489.2023.2223243. Online ahead of print. Smell and taste dysfunction in patients infected with the Omicron variant of severe acute respiratory syndrome coronavirus-2
Yanping Chen[SUP] 1 [/SUP], Yan Geng[SUP] 1 [/SUP], Juan Jiang[SUP] 1 [/SUP], Gaoyun Xiong[SUP] 1 [/SUP], Chenyang Lei[SUP] 1 [/SUP]
Affiliations
Background: Smell and taste dysfunctions (STD) are frequently observed in patients with coronavirus disease (COVID-19).
Objectives: To investigate the clinical characteristics of STD in COVID-19 patients.
Material and methods: One-hundred six COVID-19 adult patients with the Omicron variant were enrolled. The clinical features of patients with and without STD were compared using questionnaires, laboratory tests, and imaging examinations.
Results: Of the 76 patients with smell and/or taste dysfunction, age (p = .002), vaccination time (p = .024), history of systemic diseases (p = .032), and smoking status (p = .044) were significantly different from those of the controls (n = 34). Fatigue (p = .001), headache (p = .004), myalgia (p = .047), and gastrointestinal discomfort (p = .001) were observed more frequently in these patients than in controls. The Hospital Anxiety and Depression Scale score of these patients was significantly higher than that of controls (p < .001). The taste visual assessment scale score of the STD group was significantly lower than that of the taste dysfunction group (p = .001), and perceptions of sour, sweet, and salty tastes were worse in the STD group than in the taste dysfunction group (p < .001).
Conclusions and significance: COVID-19 patients had similar changes in smell and/or taste dysfunctions and worse emotional states, possibly correlated with some factors, including age and vaccination time.
Keywords: COVID-19; Omicron variant; risk factors; smell and taste dysfunction.
. 2023 Jun 16;1-6.
doi: 10.1080/00016489.2023.2223243. Online ahead of print. Smell and taste dysfunction in patients infected with the Omicron variant of severe acute respiratory syndrome coronavirus-2
Yanping Chen[SUP] 1 [/SUP], Yan Geng[SUP] 1 [/SUP], Juan Jiang[SUP] 1 [/SUP], Gaoyun Xiong[SUP] 1 [/SUP], Chenyang Lei[SUP] 1 [/SUP]
Affiliations
- PMID: 37326433
- DOI: 10.1080/00016489.2023.2223243
Background: Smell and taste dysfunctions (STD) are frequently observed in patients with coronavirus disease (COVID-19).
Objectives: To investigate the clinical characteristics of STD in COVID-19 patients.
Material and methods: One-hundred six COVID-19 adult patients with the Omicron variant were enrolled. The clinical features of patients with and without STD were compared using questionnaires, laboratory tests, and imaging examinations.
Results: Of the 76 patients with smell and/or taste dysfunction, age (p = .002), vaccination time (p = .024), history of systemic diseases (p = .032), and smoking status (p = .044) were significantly different from those of the controls (n = 34). Fatigue (p = .001), headache (p = .004), myalgia (p = .047), and gastrointestinal discomfort (p = .001) were observed more frequently in these patients than in controls. The Hospital Anxiety and Depression Scale score of these patients was significantly higher than that of controls (p < .001). The taste visual assessment scale score of the STD group was significantly lower than that of the taste dysfunction group (p = .001), and perceptions of sour, sweet, and salty tastes were worse in the STD group than in the taste dysfunction group (p < .001).
Conclusions and significance: COVID-19 patients had similar changes in smell and/or taste dysfunctions and worse emotional states, possibly correlated with some factors, including age and vaccination time.
Keywords: COVID-19; Omicron variant; risk factors; smell and taste dysfunction.