tetano
Editor, Senior Moderator
Rev Soc Bras Med Trop. 2015 Aug;48(4):498-500. doi: 10.1590/0037-8682-0314-2014.
[h=1]Acute disseminated encephalomyelitis following inactivated influenza vaccination in the Brazilian Amazon: a case report.[/h] Andrade SD[SUP]1[/SUP], Andrade MG[SUP]1[/SUP], Santos PJ[SUP]1[/SUP], Galv?o Mde L[SUP]1[/SUP], Barros MM[SUP]1[/SUP], Ramasawmy R[SUP]1[/SUP], Safe IP[SUP]1[/SUP], Monteiro WM[SUP]1[/SUP], Sabid? M[SUP]1[/SUP], Alecrim Md[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Here, we describe a case of acute disseminated encephalomyelitis (ADEM) that occurred during a plausible risk interval following inactivated influenza vaccination in a previously healthy 27-year-old man from Manaus, Brazil. He was treated with intravenous methylprednisolone and immunoglobulin. One-month follow-up revealed resolution of the brain lesions, but not of the spinal cord lesions. No recurrence or progression of the main neurological symptoms was observed. After two years of monitoring, the patient continues to experience weak lower limbs and urinary retention. Thus, we recommend that ADEM should be considered in a patient presenting with neurological symptoms after influenza vaccination.
PMID: 26312942 [PubMed - in process]
[h=1]Acute disseminated encephalomyelitis following inactivated influenza vaccination in the Brazilian Amazon: a case report.[/h] Andrade SD[SUP]1[/SUP], Andrade MG[SUP]1[/SUP], Santos PJ[SUP]1[/SUP], Galv?o Mde L[SUP]1[/SUP], Barros MM[SUP]1[/SUP], Ramasawmy R[SUP]1[/SUP], Safe IP[SUP]1[/SUP], Monteiro WM[SUP]1[/SUP], Sabid? M[SUP]1[/SUP], Alecrim Md[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Here, we describe a case of acute disseminated encephalomyelitis (ADEM) that occurred during a plausible risk interval following inactivated influenza vaccination in a previously healthy 27-year-old man from Manaus, Brazil. He was treated with intravenous methylprednisolone and immunoglobulin. One-month follow-up revealed resolution of the brain lesions, but not of the spinal cord lesions. No recurrence or progression of the main neurological symptoms was observed. After two years of monitoring, the patient continues to experience weak lower limbs and urinary retention. Thus, we recommend that ADEM should be considered in a patient presenting with neurological symptoms after influenza vaccination.
PMID: 26312942 [PubMed - in process]