tetano
Editor, Senior Moderator
Acute Med Surg
. 2022 Feb 16;9(1):e737.
doi: 10.1002/ams2.737. eCollection Jan-Dec 2022.
Two cases of multisystem inflammatory syndrome in adults after improvement in severe acute respiratory distress syndrome due to coronavirus disease 2019
Tatsuki Nonaka[SUP] 1 [/SUP], Naofumi Bunya[SUP] 1 [/SUP], Ryuichi Nakayama[SUP] 1 [/SUP], Shunya Hagiwara[SUP] 1 [/SUP], Shuji Uemura[SUP] 1 [/SUP], Keisuke Harada[SUP] 1 [/SUP], Eichi Narimatsu[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Multisystem inflammatory syndrome in adults (MIS-A) is a postacute coronavirus disease 2019 (COVID-19) syndrome occurring weeks after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Although this hyperinflammatory syndrome causes significant morbidity, mortality is low. Reports of MIS-A following acute respiratory distress syndrome (ARDS) due to SARS-CoV-2 infection have rarely been reported. We describe two cases of MIS-A that developed after recovery from critical acute COVID-19.
Case presentation: We present two cases of MIS-A. In both cases, approximately 4 weeks after the onset of COVID-19, the patients developed gastrointestinal disorders, complicated by other organ damage, and died.
Conclusion: ARDS and MIS-A can occur in a patient with COVID-19 at different times of onset. Clinicians should consider MIS-A when unexplained multisystemic abnormalities are noted after the treatment of ARDS due to COVID-19.
Keywords: Acute respiratory distress syndrome; coronavirus disease 2019; extracorporeal membrane oxygenation; gastrointestinal disturbance; multisystem inflammatory syndrome in adults.
. 2022 Feb 16;9(1):e737.
doi: 10.1002/ams2.737. eCollection Jan-Dec 2022.
Two cases of multisystem inflammatory syndrome in adults after improvement in severe acute respiratory distress syndrome due to coronavirus disease 2019
Tatsuki Nonaka[SUP] 1 [/SUP], Naofumi Bunya[SUP] 1 [/SUP], Ryuichi Nakayama[SUP] 1 [/SUP], Shunya Hagiwara[SUP] 1 [/SUP], Shuji Uemura[SUP] 1 [/SUP], Keisuke Harada[SUP] 1 [/SUP], Eichi Narimatsu[SUP] 1 [/SUP]
Affiliations
- PMID: 35223045
- PMCID: PMC8849101
- DOI: 10.1002/ams2.737
Abstract
Background: Multisystem inflammatory syndrome in adults (MIS-A) is a postacute coronavirus disease 2019 (COVID-19) syndrome occurring weeks after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Although this hyperinflammatory syndrome causes significant morbidity, mortality is low. Reports of MIS-A following acute respiratory distress syndrome (ARDS) due to SARS-CoV-2 infection have rarely been reported. We describe two cases of MIS-A that developed after recovery from critical acute COVID-19.
Case presentation: We present two cases of MIS-A. In both cases, approximately 4 weeks after the onset of COVID-19, the patients developed gastrointestinal disorders, complicated by other organ damage, and died.
Conclusion: ARDS and MIS-A can occur in a patient with COVID-19 at different times of onset. Clinicians should consider MIS-A when unexplained multisystemic abnormalities are noted after the treatment of ARDS due to COVID-19.
Keywords: Acute respiratory distress syndrome; coronavirus disease 2019; extracorporeal membrane oxygenation; gastrointestinal disturbance; multisystem inflammatory syndrome in adults.