tetano
Editor, Senior Moderator
Ann Agric Environ Med. 2013 Dec 19;20(4):820-2.
Acute respiratory distress syndrome (ARDS) complicating influenza A/H1N1v infection - a clinical approach.
Witczak A1, Prystupa A1, Kurys-Denis E2, Borys M3, Czuczwar M3, Niemcewicz M4, Kocik J4, Michalak A5, Pietrzak A5, Chodorowska G5, Krupski W2, Mosiewicz J1, Tomasiewicz K6.
Author information
Abstract
ARDS is defined as an acute inflammatory syndrome characterized with bilateral parenchymal lung infiltrates on chest radiograph and PaO2/FiO2 ratio<200 resulting from causes other than acute left ventricular dysfunction. Inflammatory lung lesions may be induced by different disorders, with sepsis being the leading cause of ARDS. Other causes include infectious pneumonia, aspiration of gastric contents, drugs, severe trauma, fat embolism, surface burn, massive blood transfusion. Influenza A/H1N1 infection seems to be responsible for the development of extremely severe type of ARDS with poor response to routine treatment. Despite great progress in the management of ARDS with novel agents and sophisticated techniques, including antimicrobial drugs, extracorporeal membrane oxygenation, prostaglandins, nitric oxide, prostacyclin, exogenous surfactant administration and activated protein C, supportive treatment based mostly on advanced mechanical ventilation in the intensive care units seems to be the most important for the prognosis.
PMID:
24364461
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/24364461
Acute respiratory distress syndrome (ARDS) complicating influenza A/H1N1v infection - a clinical approach.
Witczak A1, Prystupa A1, Kurys-Denis E2, Borys M3, Czuczwar M3, Niemcewicz M4, Kocik J4, Michalak A5, Pietrzak A5, Chodorowska G5, Krupski W2, Mosiewicz J1, Tomasiewicz K6.
Author information
Abstract
ARDS is defined as an acute inflammatory syndrome characterized with bilateral parenchymal lung infiltrates on chest radiograph and PaO2/FiO2 ratio<200 resulting from causes other than acute left ventricular dysfunction. Inflammatory lung lesions may be induced by different disorders, with sepsis being the leading cause of ARDS. Other causes include infectious pneumonia, aspiration of gastric contents, drugs, severe trauma, fat embolism, surface burn, massive blood transfusion. Influenza A/H1N1 infection seems to be responsible for the development of extremely severe type of ARDS with poor response to routine treatment. Despite great progress in the management of ARDS with novel agents and sophisticated techniques, including antimicrobial drugs, extracorporeal membrane oxygenation, prostaglandins, nitric oxide, prostacyclin, exogenous surfactant administration and activated protein C, supportive treatment based mostly on advanced mechanical ventilation in the intensive care units seems to be the most important for the prognosis.
PMID:
24364461
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/24364461