tetano
Editor, Senior Moderator
Adv Biomed Res
. 2020 Nov 28;9:71.
doi: 10.4103/abr.abr_190_20. eCollection 2020.
Thrombotic Thrombocytopenic Purpura with Conjunctivitis in a Patient with Coronavirus Disease 2019 Infection
Gholamali Dorooshi[SUP] 1 [/SUP], Sahar Sadat Lalehzar[SUP] 1 [/SUP], Maryam Nasri[SUP] 2 [/SUP], Rokhsareh Meamar[SUP] 1 [/SUP]
Affiliations
Abstract
An 81-year-old female presented with a loss of consciousness and a history of fever, dry cough, dyspnea, and conjunctivitis during 5 days ago. On initial physical examination, the laboratory examination revealed high levels of lactate dehydrogenase and creatinine concomitant severe thrombocytopenia. Moreover, the peripheral blood smear showed schistocytes 3%, suggesting thrombotic thrombocytopenic purpura (TTP). A ground-glass pattern was reported in the high-resolution computed tomography of the lung. A positive polymerase chain reaction was reported for coronavirus disease 2019 (COVID-19). After initiating treatment for COVID-19, the patient received fresh frozen plasma and 24-h electrocardiogram monitoring in the emergency department. As the patient was being prepared for transfer to another hospital for plasmapheresis treatment, cardiac arrest occurred again, and the patient passed away. This study highlights the atypical behavior of this virus over the course of the disease including TTP with conjunctivitis, which could vary from case to case.
Keywords: Conjunctivitis; coronavirus disease 2019; thrombocytopenia.
. 2020 Nov 28;9:71.
doi: 10.4103/abr.abr_190_20. eCollection 2020.
Thrombotic Thrombocytopenic Purpura with Conjunctivitis in a Patient with Coronavirus Disease 2019 Infection
Gholamali Dorooshi[SUP] 1 [/SUP], Sahar Sadat Lalehzar[SUP] 1 [/SUP], Maryam Nasri[SUP] 2 [/SUP], Rokhsareh Meamar[SUP] 1 [/SUP]
Affiliations
- PMID: 33816390
- PMCID: PMC8012864
- DOI: 10.4103/abr.abr_190_20
Abstract
An 81-year-old female presented with a loss of consciousness and a history of fever, dry cough, dyspnea, and conjunctivitis during 5 days ago. On initial physical examination, the laboratory examination revealed high levels of lactate dehydrogenase and creatinine concomitant severe thrombocytopenia. Moreover, the peripheral blood smear showed schistocytes 3%, suggesting thrombotic thrombocytopenic purpura (TTP). A ground-glass pattern was reported in the high-resolution computed tomography of the lung. A positive polymerase chain reaction was reported for coronavirus disease 2019 (COVID-19). After initiating treatment for COVID-19, the patient received fresh frozen plasma and 24-h electrocardiogram monitoring in the emergency department. As the patient was being prepared for transfer to another hospital for plasmapheresis treatment, cardiac arrest occurred again, and the patient passed away. This study highlights the atypical behavior of this virus over the course of the disease including TTP with conjunctivitis, which could vary from case to case.
Keywords: Conjunctivitis; coronavirus disease 2019; thrombocytopenia.