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Aging, cytomegalovirus (CMV) and influenza vaccine responses

tetano

Editor, Senior Moderator
Hum Vaccin Immunother. 2015 Nov 20:0. [Epub ahead of print]
[h=1]Aging, cytomegalovirus (CMV) and influenza vaccine responses.[/h] Frasca D[SUP]1[/SUP], Blomberg BB[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have identified immune biomarkers able to predict a protective humoral immune response to the vaccine. In this review, we summarize current knowledge on the effects of aging on influenza vaccine responses and on biomarkers so far identified, and we discuss the relevance of latent cytomegalovirus (CMV) infection on these vaccine responses.


[h=4]KEYWORDS:[/h] Aging; B cells; CMV; influenza vaccine

PMID: 26588038 [PubMed - as supplied by publisher]
 
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