tetano
Editor, Senior Moderator
AJNR Am J Neuroradiol
. 2020 Jul 30.
doi: 10.3174/ajnr.A6679. Online ahead of print.
Pressing Issues in COVID-19: Probable Cause to Seize SARS-CoV-2 for Its Preferential Involvement of Posterior Circulation Manifesting as Severe Posterior Reversible Encephalopathy Syndrome and Posterior Strokes
F D'Amore[SUP] 1 [/SUP], G Vinacci[SUP] 2 [/SUP], E Agosti[SUP] 3 [/SUP], L P Cariddi[SUP] 4 5 [/SUP], A V Terrana[SUP] 1 [/SUP], F A Vizzari[SUP] 1 [/SUP], M Mauri[SUP] 4 [/SUP], A Giorgianni[SUP] 1 [/SUP]
Affiliations
Abstract
Since December 2019, a novel Severe Acute Respiratory Syndrome coronavirus 2 from China has rapidly spread worldwide. Although respiratory involvement is the mainstay of coronavirus disease 2019 (COVID-19), systemic involvement has recently drawn more attention. In particular, a number of recent articles have shed light on the nervous system as one of the possible targets. At our institution, we observed 15 patients with acute brain vascular manifestations; most interesting, we had a higher prevalence of the posterior circulation acute impairment. In our series, 7 patients had acute posterior cerebral injury: 1, hemorrhagic posterior reversible encephalopathy syndrome; 5, posterior circulation ischemic stroke; and 1, parieto-occipital hemorrhagic stroke. On the basis of our evidence and previous basic science reports, we believe a common etiopathogenetic thread may connect ischemic/hemorrhagic events of the posterior circulation and posterior reversible encephalopathy syndrome in the setting of COVID-19.
. 2020 Jul 30.
doi: 10.3174/ajnr.A6679. Online ahead of print.
Pressing Issues in COVID-19: Probable Cause to Seize SARS-CoV-2 for Its Preferential Involvement of Posterior Circulation Manifesting as Severe Posterior Reversible Encephalopathy Syndrome and Posterior Strokes
F D'Amore[SUP] 1 [/SUP], G Vinacci[SUP] 2 [/SUP], E Agosti[SUP] 3 [/SUP], L P Cariddi[SUP] 4 5 [/SUP], A V Terrana[SUP] 1 [/SUP], F A Vizzari[SUP] 1 [/SUP], M Mauri[SUP] 4 [/SUP], A Giorgianni[SUP] 1 [/SUP]
Affiliations
- PMID: 32732268
- DOI: 10.3174/ajnr.A6679
Abstract
Since December 2019, a novel Severe Acute Respiratory Syndrome coronavirus 2 from China has rapidly spread worldwide. Although respiratory involvement is the mainstay of coronavirus disease 2019 (COVID-19), systemic involvement has recently drawn more attention. In particular, a number of recent articles have shed light on the nervous system as one of the possible targets. At our institution, we observed 15 patients with acute brain vascular manifestations; most interesting, we had a higher prevalence of the posterior circulation acute impairment. In our series, 7 patients had acute posterior cerebral injury: 1, hemorrhagic posterior reversible encephalopathy syndrome; 5, posterior circulation ischemic stroke; and 1, parieto-occipital hemorrhagic stroke. On the basis of our evidence and previous basic science reports, we believe a common etiopathogenetic thread may connect ischemic/hemorrhagic events of the posterior circulation and posterior reversible encephalopathy syndrome in the setting of COVID-19.