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Am J Clin Pathol . Investigation of SARS-CoV-2 Epsilon Variant and Hospitalization Status by Genomic Surveillance in a Single Large Health System D

tetano

Editor, Senior Moderator
Am J Clin Pathol


. 2021 Dec 7;aqab203.
doi: 10.1093/ajcp/aqab203. Online ahead of print.
Investigation of SARS-CoV-2 Epsilon Variant and Hospitalization Status by Genomic Surveillance in a Single Large Health System During the 2020-2021 Winter Surge in Southern California


Shangxin Yang[SUP] 1 [/SUP], Peera Hemarajata[SUP] 2 [/SUP], Evann E Hilt[SUP] 1 [/SUP], Travis K Price[SUP] 1 [/SUP], Omai B Garner[SUP] 1 [/SUP], Nicole M Green[SUP] 2 [/SUP]



Affiliations

Abstract

Objectives: This study aimed to assess whether the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Epsilon variant (B.1.429/427) is more virulent, leading to more hospitalization and more severe disease requiring intensive care unit (ICU) admission.
Methods: SARS-CoV-2 genomic surveillance was performed on respiratory samples from 231 unique patients, collected at a single large health system in Southern California between November 2020 and March 2021 during the winter surge.
Results: The frequencies of the Epsilon variant among outpatients, hospitalized patients, and ICU patients were indifferent.
Conclusions: Our study suggests that the Epsilon variant is not associated with increased hospitalization and ICU admission.

Keywords: B.1.427; B.1.429; COVID-19; California; Epsilon variant; Genomic surveillance; Hospitalization; ICU; SARS-CoV-2.
 
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