tetano
Editor, Senior Moderator
Am J Kidney Dis
. 2022 Jun 15;S0272-6386(22)00720-X.
doi: 10.1053/j.ajkd.2022.04.011. Online ahead of print.
Vaccine Attitudes and COVID-19 Vaccine Intention Among Parents of Children With Kidney Disease or Primary Hypertension
Chia-Shi Wang[SUP] 1 [/SUP], Rinchen Doma[SUP] 2 [/SUP], Adrianna L Westbrook[SUP] 3 [/SUP], Jillian Johnson[SUP] 2 [/SUP], Evan J Anderson[SUP] 3 [/SUP], Larry A Greenbaum[SUP] 3 [/SUP], Shaheen A Rana[SUP] 4 [/SUP], Roshan P George[SUP] 3 [/SUP], Rouba Garro[SUP] 3 [/SUP], Anjali Khanna-Farber[SUP] 3 [/SUP], Cam Escoffery[SUP] 2 [/SUP], Robert A Bednarczyk[SUP] 5 [/SUP]
Affiliations
Abstract
Rationale & objective: Children with kidney disease and primary hypertension may be more vulnerable to COVID-19 disease. We examined COVID-19 vaccine hesitancy among parents of children with CKD or hypertension.
Study design: Sequential explanatory mixed-methods design; survey followed by in-depth interviews.
Setting & participants: Parents of children <18 years with kidney disease or primary hypertension within a large pediatric practice.
Exposures: Parental attitudes towards general childhood and influenza vaccines assessed by the Vaccine Hesitancy Scale. Kidney disease classification, demographic and socioeconomic factors, COVID-19 disease experiences, COVID-19 mitigation activities and self-efficacy, and sources of vaccine information.
Outcomes: Willingness to vaccinate child against COVID-19.
Analytical approach: ANOVA test to compare parental attitudes towards general childhood and influenza vaccination with attitudes toward COVID-19 vaccination. Multinomial logistic regression to assess predictors of willingness to vaccinate against COVID-19. Thematic analysis of interview data to characterize influences on parental attitudes.
Results: 207 parents completed the survey (39% of approached): 75 (36%) were willing, 80 (39%) unsure, and 52 (25%) unwilling to vaccinate their child against COVID-19. Hesitancy towards general childhood and influenza vaccines was highest among the unwilling group (p<0.001). More highly educated parents more likely to be willing to vaccinate their children, while Black race was associated with being more likely to be unwilling. Rushed COVID vaccine development as well as fear of serious and unknown long-term side effects were themes that differed across the parental groups willing, unsure, or unwilling to vaccinate their children. While doctors and healthcare teams are trusted sources of vaccine information, perceptions of benefit versus harm and experiences with doctors differed among these three groups. The need for additional information on COVID-19 vaccines was greatest among those unwilling or unsure about vaccinating.
Limitations: Generalizability may be limited.
Conclusions: Two-thirds of parents of children with kidney disease or hypertension were unsure or unwilling to vaccinate their child against COVID-19. Higher hesitancy towards routine childhood and influenza vaccination was associated with hesitancy towards COVID-19 vaccines.. Enhanced communication of vaccine information relevant to kidney patients in an accessible manner should be examined as a means to reduce vaccine hesitancy.
Keywords: COVID-19; COVID-19 Vaccine Hesitancy; Child; Glomerular Diseases; Hypertension; Influenza Vaccines; Kidney Diseases; Qualitative Research; Vaccination; Vaccination Hesitancy.
. 2022 Jun 15;S0272-6386(22)00720-X.
doi: 10.1053/j.ajkd.2022.04.011. Online ahead of print.
Vaccine Attitudes and COVID-19 Vaccine Intention Among Parents of Children With Kidney Disease or Primary Hypertension
Chia-Shi Wang[SUP] 1 [/SUP], Rinchen Doma[SUP] 2 [/SUP], Adrianna L Westbrook[SUP] 3 [/SUP], Jillian Johnson[SUP] 2 [/SUP], Evan J Anderson[SUP] 3 [/SUP], Larry A Greenbaum[SUP] 3 [/SUP], Shaheen A Rana[SUP] 4 [/SUP], Roshan P George[SUP] 3 [/SUP], Rouba Garro[SUP] 3 [/SUP], Anjali Khanna-Farber[SUP] 3 [/SUP], Cam Escoffery[SUP] 2 [/SUP], Robert A Bednarczyk[SUP] 5 [/SUP]
Affiliations
- PMID: 35750280
- PMCID: PMC9212850
- DOI: 10.1053/j.ajkd.2022.04.011
Abstract
Rationale & objective: Children with kidney disease and primary hypertension may be more vulnerable to COVID-19 disease. We examined COVID-19 vaccine hesitancy among parents of children with CKD or hypertension.
Study design: Sequential explanatory mixed-methods design; survey followed by in-depth interviews.
Setting & participants: Parents of children <18 years with kidney disease or primary hypertension within a large pediatric practice.
Exposures: Parental attitudes towards general childhood and influenza vaccines assessed by the Vaccine Hesitancy Scale. Kidney disease classification, demographic and socioeconomic factors, COVID-19 disease experiences, COVID-19 mitigation activities and self-efficacy, and sources of vaccine information.
Outcomes: Willingness to vaccinate child against COVID-19.
Analytical approach: ANOVA test to compare parental attitudes towards general childhood and influenza vaccination with attitudes toward COVID-19 vaccination. Multinomial logistic regression to assess predictors of willingness to vaccinate against COVID-19. Thematic analysis of interview data to characterize influences on parental attitudes.
Results: 207 parents completed the survey (39% of approached): 75 (36%) were willing, 80 (39%) unsure, and 52 (25%) unwilling to vaccinate their child against COVID-19. Hesitancy towards general childhood and influenza vaccines was highest among the unwilling group (p<0.001). More highly educated parents more likely to be willing to vaccinate their children, while Black race was associated with being more likely to be unwilling. Rushed COVID vaccine development as well as fear of serious and unknown long-term side effects were themes that differed across the parental groups willing, unsure, or unwilling to vaccinate their children. While doctors and healthcare teams are trusted sources of vaccine information, perceptions of benefit versus harm and experiences with doctors differed among these three groups. The need for additional information on COVID-19 vaccines was greatest among those unwilling or unsure about vaccinating.
Limitations: Generalizability may be limited.
Conclusions: Two-thirds of parents of children with kidney disease or hypertension were unsure or unwilling to vaccinate their child against COVID-19. Higher hesitancy towards routine childhood and influenza vaccination was associated with hesitancy towards COVID-19 vaccines.. Enhanced communication of vaccine information relevant to kidney patients in an accessible manner should be examined as a means to reduce vaccine hesitancy.
Keywords: COVID-19; COVID-19 Vaccine Hesitancy; Child; Glomerular Diseases; Hypertension; Influenza Vaccines; Kidney Diseases; Qualitative Research; Vaccination; Vaccination Hesitancy.